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Displaying results 8311 - 8320 of 10000 in total
  1. Drug

    Vudalimab

    go.drugbank.com/drugs/DB18833
    Investigational

    Vudalimab is under investigation in clinical trial NCT05005728 (Xmab®20717 (Vudalimab) Alone or in Combination With Chemotherapy or Targeted Therapy in Patients With Metastatic Castration-resistant Prostate

    Synonyms: Immunoglobulin half-ig g1-kappa/scfv-h-ch2-ch3, anti-(homo sapiens ctla4 (cytotoxic t-lymphocyte-associated protein 4, cd152)) and anti-(homo sapienspdcd1 (programmed cell death 1, pd-1, pd1, cd279)),
  2. Drug

    Iclepertin

    go.drugbank.com/drugs/DB19058
    Investigational

    Iclepertin is under investigation in clinical trial NCT05211947 (A Study to Test Long-term Safety of Iclepertin in People With Schizophrenia Who Took Part in a Previous CONNEX Study).

  3. Drug

    Esaxerenone

    go.drugbank.com/drugs/DB15207
    Investigational

    Esaxerenone is under investigation in clinical trial NCT02722265 (Long-term Study of CS-3150 as Monotherapy or in Combination With Other Antihypertensive Drug in Japanese Patients With Essential Hypertension

  4. Drug

    Balcinrenone

    go.drugbank.com/drugs/DB15418
    Investigational

    AZD-9977 is under investigation in clinical trial NCT03843060 (A Phase 1 Study to Assess the Pharmacokinetics of AZD9977 Administered Alone and in Combination With Itraconazole in Healthy Volunteers).

  5. Drug

    Nisevokitug

    go.drugbank.com/drugs/DB17561
    Investigational

    and Efficacy of Novel Ruxolitinib Combinations in Myelofibrosis Patients). … Nisevokitug is a monoclonal antibody targeted against transforming growth factor beta (TGFβ) under investigation in NCT04097821 (A Randomized, Open-label, Phase I/II Open Platform Study Evaluating Safety

  6. Drug

    Quisovalimab

    go.drugbank.com/drugs/DB16482
    Investigational

  7. Drug

    Abdavomeran

    go.drugbank.com/drugs/DB15695
    Investigational

    [L15012] BNT162b1 is undergoing further evaluation in clinical trials in both the USA (NCT04368728) and Germany (NCT04380701). … [L15012] The modRNA is formulated in lipid nanoparticles for delivery via intramuscular injection.

  8. Drug

    Asapiprant

    go.drugbank.com/drugs/DB20492
    Investigational

    Are Not in Respiratory Failure). … Asapiprant is under investigation in clinical trial NCT04705597 (Study to Evaluate the Safety, Tolerability, and Efficacy of BGE-175 in Hospitalized Adults With Coronavirus Disease 2019 (COVID-19) That

  9. Drug

    BGB-DXP593

    go.drugbank.com/drugs/DB16357
    Investigational

    [L27401] It is currently being investigated against COVID-19 in the clinical trial NCT04551898 (Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Neutralizing Antibody BGB-DXP593 in Participants … BGB-DXP593 is a SARS-CoV-2 neutralizing antibody.

  10. Drug

    Methylmalonic Acid

    go.drugbank.com/drugs/DB04183
    Experimental

    A malonic acid derivative which is a vital intermediate in the metabolism of fat and protein. Abnormalities in methylmalonic acid metabolism lead to methylmalonic aciduria. … This metabolic disease is attributed to a block in the enzymatic conversion of methylmalonyl CoA to succinyl CoA. [PubChem]