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S-777469
go.drugbank.com/drugs/DB16321InvestigationalS-777469 is under investigation in clinical trial NCT00703573 (A Randomized, Double-blind Study to Evaluate the Safety and Efficacy of 2 Doses of S-777469 in Patients With Atopic Dermatitis).
Categories: Heterocyclic Compounds, 1-RingSimurosertib
go.drugbank.com/drugs/DB16330InvestigationalSimurosertib is under investigation in clinical trial NCT03261947 (A Study to Evaluate the Safety, Tolerability, and Activity of TAK-931 in Participants With Metastatic Pancreatic Cancer, Metastatic Colorectal
Categories: Heterocyclic Compounds, 1-RingSynonyms: 2-[(2S)-1-azabicyclo[2.2.2]oct-2-yl]-6-(3-methyl-1H-pyrazol-4-yl)thieno[3,2-d]pyrimidin-4(3H)-oneSodelglitazar
go.drugbank.com/drugs/DB16332InvestigationalSodelglitazar is under investigation in clinical trial NCT00196989 (Study in People With Type 2 Diabetes).
Sulopenem etzadroxil
go.drugbank.com/drugs/DB16335ApprovedInvestigationalSulopenem etzadroxil is a prodrug of the penem antibacterial [sulopenem]. Like other beta-lactam antibacterials, it is a time-dependent inhibitor of bacterial cell wall synthesis.
Trastuzumab duocarmazine
go.drugbank.com/drugs/DB16342InvestigationalTrastuzumab duocarmazine is under investigation in clinical trial NCT03262935 (SYD985 vs. Physician's Choice in Participants With Her2-positive Locally Advanced or Metastatic Breast Cancer).
Synonyms: Immunoglobulin g1-kappa, anti-(homo sapiens erbb2 (epidermal growth factor receptor 2, receptor tyrosineprotein kinase erbb-2, egfr2, her2, her-2, p185cerbb2, neu, cd340)), humanized monoclonal antibodyCategories: HER2 (Human Epidermal Growth Factor Receptor 2) inhibitorsViagenpumatucel-L
go.drugbank.com/drugs/DB16348InvestigationalViagenpumatucel-L is under investigation in clinical trial NCT02117024 (A Phase 2 Study of Viagenpumatucel-l (HS-110) in Patients With Non-small Cell Lung Cancer).
Synonyms: Viagenpumatucel l, Viagenpumatucel-LVicagrel
go.drugbank.com/drugs/DB16349InvestigationalVicagrel is under investigation in clinical trial NCT03599284 (The Efficacy, Safety and Pharmacokinetic of Antiplatelet Therapy for Vicagrel).
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingAvasopasem manganese
go.drugbank.com/drugs/DB16354InvestigationalAvasopasem manganese, also known as GC4419, is a highly-selective small molecule mimetic of superoxide dismutase (SOD) being investigated for the reduction of radiation-induced severe oral mucositis.
Anti-SARS-CoV-2 IgY
go.drugbank.com/drugs/DB16356Investigational-2) Chicken Egg Antibody (IgY) (COVID-19)). … Anti-SARS-CoV-2 IgY are chicken egg antibodies to SARS-CoV-2 which have the potential to provide temporary protection against the virus when administered as intranasal drops.
Synonyms: Anti-Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Chicken Egg Antibody (IgY)