Siremadlin

DB16331InvestigationalSmall molecule

Siremadlin: Overview.

Chemical structure of Siremadlin
Formula / weight
C26H24Cl2N6O4 · 555.42 g/mol (avg)
Code names
HDM 201 · NVP-HDM 201

Resolves to

Compound
UNII0282IF4JC8CAS1448867-41-1ChEMBLCHEMBL3653256
Structure
InChIKeyAGBSXNCBIWWLHD-FQEVSTJZSA-NSMILESCOC1=NC(OC)=C(C=N1)C1=NC2=C([C@@H](N(C2=O)C2=CC(Cl)=CN(C)C2=O)C2=CC=C(Cl)C=C2)N1C(C)C
Targets
Q00987MDM2P04637TP53

What you can answer from here — as of September 24, 2025

2Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
14Clinical trialsPhase, status and sponsor resolved per trial
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2+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Siremadlin, and which of those have an active Phase 3 trial?

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