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Displaying results 8361 - 8370 of 10000 in total
  1. Drug

    Aldafermin

    go.drugbank.com/drugs/DB16086
    Investigational

    Aldafermin is under investigation in clinical trial NCT03912532 (Evaluation of Efficacy, Safety and Tolerability of Aldafermin in a Phase 2b, Randomized, Double-blind, Placebo-controlled, Multi-center

    Synonyms: Engineered variant of recombinant human fibroblast growth factor 19
  2. Drug

    IDM-1

    go.drugbank.com/drugs/DB05292
    Experimental

    IDM-1 is IDM’s most advanced antibody-based Cell drug for the treatment of cancer. … It is comprised of MAK(Monocytes-derived Activated Killer) cells associated with MDX-210, a bispecific anti-HER-2/neu antibody developed by Medarex Inc.

  3. Drug

    MF-300

    go.drugbank.com/drugs/DB32060
    Investigational

    MF-300 is an investigational, first-in-class, small molecule inhibitor of 15-hydroxyprostaglandin dehydrogenase. … As a potential candidate for the treatment of sarcopenia, it has undergone phase 1 studies to evaluate safety, tolerability, and PK/PD characteristics.[A275368,L54983]

  4. Drug

    Picafibrate

    go.drugbank.com/drugs/DB19574
    Experimental

    Picafibrate has a monoisotopic molecular weight of 362.1 Da. … The usage of the INN stem '-fibrate' in the name indicates that Picafibrate is a clofibrate derivative, peroxisome proliferator activated receptor-a (PPAR-a) agonist.

  5. Drug

    Tiafibrate

    go.drugbank.com/drugs/DB19874
    Experimental

    Tiafibrate has a monoisotopic molecular weight of 686.23 Da. … The usage of the INN stem '-fibrate' in the name indicates that Tiafibrate is a clofibrate derivative, peroxisome proliferator activated receptor-a (PPAR-a) agonist.

  6. Drug

    Urefibrate

    go.drugbank.com/drugs/DB20849
    Experimental

    Urefibrate has a monoisotopic molecular weight of 354.02 Da. … The usage of the INN stem '-fibrate' in the name indicates that Urefibrate is a clofibrate derivative, peroxisome proliferator activated receptor-a (PPAR-a) agonist.

  7. Drug

    Sitofibrate

    go.drugbank.com/drugs/DB21192
    Experimental

    Sitofibrate has a monoisotopic molecular weight of 610.42 Da. … The usage of the INN stem '-fibrate' in the name indicates that Sitofibrate is a clofibrate derivative, peroxisome proliferator activated receptor-a (PPAR-a) agonist.

  8. Drug

    Ninerafaxstat

    go.drugbank.com/drugs/DB21486
    Investigational

    Ninerafaxstat has a monoisotopic molecular weight of 415.21 Da. … Ninerafaxstat is under investigation in clinical trial NCT07023614 (A Trial to Evaluate the Efficacy and Safety of Ninerafaxstat in Patients With Symptomatic Non-obstructive Hypertrophic Cardiomyopathy

  9. Drug

    Zatonacaftor

    go.drugbank.com/drugs/DB21625
    Experimental

    Zatonacaftor has a monoisotopic molecular weight of 453.17 Da. … The usage of the INN stem '-caftor' in the name indicates that Zatonacaftor is a Cystic fibrosis transmembrane regulator (CFTR) protein modulator, corrector, and amplifier.

  10. Drug

    Zilpaterol

    go.drugbank.com/drugs/DB11479
    ExperimentalVet approved

    Zilpaterol is a β2 adrenergic agonist sold under the trade name, Zilmax, produced by Intervet, a subsidiary of Merck & Co. … Zilpaterol is typically fed to cattle in the last three to six weeks of life with a brief washout period to clear the drug from the tissues before slaughter.