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Displaying results 8361 - 8370 of 10000 in total
  1. Drug

    Nanrilkefusp alfa

    go.drugbank.com/drugs/DB17480
    Investigational

    Nanrilkefusp alfa is a human fusion protein consisting of the cytokine interleukin (IL)-15 and the high-affinity binding sushi+ domain of IL-15 receptor alpha (IL-15Ra).

  2. Drug

    BI-765063

    go.drugbank.com/drugs/DB17482
    Investigational

    BI-765063 is a humanized IgG4 monoclonal antibody antagonist of signal regulatory protein α (SIRPα).

  3. Drug

    PF-07799933

    go.drugbank.com/drugs/DB17489
    Investigational

    PF-07799933 is a BRAF class 2 inhibitor developed by Pfizer.

  4. Drug

    CGX-1321

    go.drugbank.com/drugs/DB17491
    Investigational

    CGX-1321 is a porcupine inhibitor that affects Wnt production and can block Wnt downstream signaling.[A257038]

  5. Drug

    SB 11285

    go.drugbank.com/drugs/DB17511
    Investigational

    SB 11285 is a second-generation Stimulator of Interferon Genes (STING) agonist.

  6. Drug

    Ligufalimab

    go.drugbank.com/drugs/DB17542
    Investigational

    Ligufalimab is a humanized immunoglobulin G4 (IgG4) monoclonal antibody targeting leukocyte surface antigen CD47. … It is under investigation in clinical trial NCT04900350 (A Trial of AK117 (Anti-cd47) in Patients With Myelodysplastic Syndrome).

  7. Drug

    FT-1101

    go.drugbank.com/drugs/DB17553
    Investigational

    FT-1101 is a novel Bromodomain and Extra-Terminal motif (BET) inhibitor. … [A257301] FT-1101 is under investigation in clinical trial NCT02543879 (Study of a Novel BET Inhibitor FT-1101 in Patients With Relapsed or Refractory Hematologic Malignancies).

  8. Drug

    FF-10501-01

    go.drugbank.com/drugs/DB17554
    Investigational

    FF-10501-01 is a novel, selective inosine monophosphate dehydrogenase (IMPDH) inhibitor with anticancer activity. … [A257306] FF-10501-01 is under investigation in clinical trial NCT03486353 (A Study of FF-10501-01 in Combination With Azacitidine in Patients With Myelodysplastic Syndrome).

  9. Drug

    Nisevokitug

    go.drugbank.com/drugs/DB17561
    Investigational

    Nisevokitug is a monoclonal antibody targeted against transforming growth factor beta (TGFβ) under investigation in NCT04097821 (A Randomized, Open-label, Phase I/II Open Platform Study Evaluating Safety

  10. Drug

    Hemoximer

    go.drugbank.com/drugs/DB17600
    Investigational

    Hemoximer is a modified version of hemoglobin that undergoes pyridoxylation, for the purpose of lowering the oxygen affinity, and coupling with polyoxyethylene (POE), to increase its molecular weight.