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Levamisole
go.drugbank.com/drugs/DB00848ApprovedInvestigationalVet approvedWithdrawn[A178117] It was manufactured by _Janssen_ and first used in 1969 as an agent to treat worm infestations[A178123] Levamisole was approved by the FDA in 1990 as an adjuvant treatment for colon cancer. … [L6232] Prior to this, levamisole was used as an antirheumatic therapy in the 1970s and 1980s for patients with rheumatoid arthritis.
Categories: Antiparasitic Products, Insecticides and RepellentsProducts: OBAT CACING NO.17 KAM CEK SAN, Ergamisol Tab 50mgAcetazolamide
go.drugbank.com/drugs/DB00819ApprovedInvestigationalVet approvedIts antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition … (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)
Synonyms: N-[5-(aminosulfonyl)-1,3,4-thiadiazol-2-yl]acetamide, N-[5-(aminosulfonyl)-1,3,5-thiadiazol-2-yl]acetamideCategories: Antiglaucoma Preparations and Miotics, Genito Urinary System and Sex HormonesPrimidone
go.drugbank.com/drugs/DB00794ApprovedVet approved[L11112] Primidone was developed by J Yule Bogue and H C Carrington in 1949.[A189522] Primidone was granted FDA Approval on 8 March 1954.[L11112] … Primidone is an anticonvulsant used to treat essential tremor as well as grand mal, psychomotor, and focal epileptic seizures.
Categories: Barbiturates and Derivatives, Hypnotics and SedativesProducts: Mysoline Tab 250mg, Mysoline 250mg TabOxybutynin
go.drugbank.com/drugs/DB01062ApprovedInvestigationalDue to its urinary symptoms that include nocturia, urgency, and frequency, this condition causes social embarrassment and a poor quality of life. … [A183782,L8648] This drug relieves undesirable urinary symptoms, increasing the quality of life for patients affected by OAB. It is often used as first-line therapy for OAB.[A185990]
Categories: Genito Urinary System and Sex Hormones, Drugs for Urinary Frequency and IncontinenceProducts: Ditropan Syrup 1mg/ml, OXYBUTYNIN HEXAL 2.5MGMetronidazole
go.drugbank.com/drugs/DB00916ApprovedInvestigational[L3754] It is frequently used to treat gastrointestinal infections as well as trichomoniasis and giardiasis, and amebiasis which are parasitic infections. … It is available in capsule form, tablet form, and topical form, and suppository preparations for the treatment of various infections.
Mixtures: METRONIDAZOL / CLOTRIMAZOL 500MG / 100MG OVULO VAGINAL, Bismuth Subcitrate Potassium, Metronidazole and Tetracycline HydrochlorideCategories: Alimentary Tract and Metabolism, metronidazole and diloxanideVarenicline
go.drugbank.com/drugs/DB01273ApprovedInvestigationalIn addition it acts on alpha3/beta4 and weakly on alpha3beta2 and alpha6-containing receptors. A full agonism was displayed on alpha7-receptors. On March 9, 2015, the U.S. … Food and Drug Administration warned that Varenicline, in the form of Pfizer Inc's quit-smoking drug, Chantix, has been associated with seizures and that some patients who drink while taking the drug may
Products: Champix Tablet 1mg, CHAMPIX 1.0MG FILM-COATED TABLETSOctasulfur
go.drugbank.com/drugs/DB09353ApprovedSulfur seems to have an antibacterial activity. It has been also used for acne. … People take sulfur by mouth for shortness of breath, allergies, swelling in the back of the throat (pharyngitis), high cholesterol, clogged arteries, menopause, and upper respiratory tract infections like
Mixtures: NW SULPHUR 2%W/W AND SALICYLIC ACID 2%W/W CREAM, POLY-N OINTMENTProducts: Malin and Goetz Acne Treatment, Sodium Sulfacetamide and SulfurAmbroxol
go.drugbank.com/drugs/DB06742ApprovedInvestigationalSurfactants acts as an anti-glue factor by reducing the adhesion of mucus to the bronchial wall, in improving its transport and in providing protection against infection and irritating agents. … It stimulates synthesis and release of surfactant by type II pneumocytes.
Synonyms: N-(2-Amino-3,4-dibromociclohexil)-trans-4-aminociclohexanol, N-(2-Amino-3,4-dibromocyclohexyl)-trans-4-aminocyclohexanolMixtures: MUCOSOLVAN®COMPOSITUM GOTAS 15MG/0.01MG/2ML, TUSIGEN NFMycophenolate mofetil
go.drugbank.com/drugs/DB00688ApprovedInvestigational[A180799,A180805] Previously, mycophenolic acid (MPA) was administered to individuals with autoimmune diseases beginning in the 1970s, but was discontinued due to gastrointestinal effects and concerns … [L7363] It is marketed by Roche Pharmaceuticals and was granted FDA approval for the prophylaxis of transplant rejection in 1995.
Categories: Mycophenolic Acid and ProdrugsProducts: Co Mycophenolate, MYFENAX 250MGClindamycin
go.drugbank.com/drugs/DB01190ApprovedInvestigationalVet approved[A190621] Interestingly, clindamycin appears to carry some activity against protozoans, and has been used off-label in the treatment of toxoplasmosis, malaria, and babesiosis. … [A190657] Clindamycin is derived from, and has largely replaced, [lincomycin], a naturally occurring lincosamide and the eponymous member of this antibiotic class, due to its improved properties over
Mixtures: CLINDAMICINA / CLOTRIMAZOL 100MG/200MG, Clindamycin and Benzoyl PeroxideCategories: Genito Urinary System and Sex Hormones, Macrolides, Lincosamides and Streptogramins