Search
Cysteamine
go.drugbank.com/drugs/DB00847ApprovedInvestigational[L15611] On August 25th 2020, the first ophthalmic solution for cystinosis requiring only 4 daily treatments was granted FDA approval. … [A218721] Several preparations of cysteamine exist for the treatment of cystinosis manifestations, some in capsule form, and others in ophthalmic solution form.
Synonyms: 2-aminoethanethiol, 2-amino-ethanethiolProducts: CYSTAGON ® 150 MG, CYSTAGON ® 50 MG CAPSULASZolpidem
go.drugbank.com/drugs/DB00425ApprovedInvestigationalIt is aimed for use in patients with difficulties initiating sleep. … It is available in both immediate acting and extended release forms [FDA label], [F3802].
Mixtures: Gabazolpidem-5, Sentrazolpidem PM-5Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesSulthiame
go.drugbank.com/drugs/DB08329ApprovedProducts: Ospolot 50 mg Filmtabletten, Sultiam neuraxpharm 100 mg FilmtablettenDanazol
go.drugbank.com/drugs/DB01406ApprovedInvestigationalIt possesses some androgenic properties. Danazol has been used in the treatment of endometriosis and some benign breast disorders. … A synthetic steroid with antigonadotropic and anti-estrogenic activities that acts as an anterior pituitary suppressant by inhibiting the pituitary output of gonadotropins.
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsProducts: DANASIN 50 MG KAPSUL, 100 ADET, DANASIN 100 MG KAPSUL, 100 ADETFebuxostat
go.drugbank.com/drugs/DB04854ApprovedInvestigationalThe manufacturer and the FDA advise health professionals to limit the use of febuxostat to second-line therapy in patients who have inadequate response or intolerance to allopurinol, and to avoid the use … [A230548] In the following year, the FDA for approved febuxostat for use in the chronic management of hyperuricemia in adult patients with gout who have an inadequate response or intolerance to [allopurinol
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesSynonyms: 2-(3-cyano-4-isobutoxyphenyl)-4-methyl- 1,3-thiazole-5-carboxylic acidCalcitriol
go.drugbank.com/drugs/DB00136ApprovedInvestigationalNutraceuticalIt is also available in topical form for the treatment of mild to moderate plaque psoriasis in adults. … Calcitriol is an active metabolite of vitamin D with 3 hydroxyl (OH) groups and is commonly referred to as 1,25-dihydroxycholecalciferol, or 1alpha,25-dihydroxyvitamin D<sub>3</sub>, 1,25-dihydroxyvitamin
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersSynonyms: 1α,25(OH)2D3, (1S,3R,5Z,7E)-9,10-secocholesta-5,7,10-triene-1,3,25-triolAntithrombin III human
go.drugbank.com/drugs/DB11598ApprovedInvestigationalA plasma alpha 2 glycoprotein that accounts for the major antithrombin activity of normal plasma and also inhibits several other enzymes. It is a member of the serpin superfamily.
Synonyms: AT-IIIProducts: ANBİNEX 1000 IU/20 ML IV İNFÜZYON İÇİN LİYOFİLİZE TOZ İÇEREN FLAKON VE ÇÖZÜCÜSÜ, ANBİNEX 500 IU/10 ML IV İNFÜZYON İÇİN LİYOFİLİZE TOZ İÇEREN FLAKON VE ÇÖZÜCÜSÜAfatinib
go.drugbank.com/drugs/DB08916ApprovedInvestigationalAfatinib is a 4-anilinoquinazoline tyrosine kinase inhibitor in the form of a dimaleate salt available as Boehringer Ingelheim's brand name Gilotrif [FDA Label]. … For oral use, afatinib tablets are a first-line (initial) treatment for patients with metastatic non-small cell lung cancer (NSCLC) with common epidermal growth factor receptor (EGFR) mutations as detected
Categories: Heterocyclic Compounds, 2-RingProducts: GIOTRIF® 50 MG, GIOTRIF® 20 MGFinerenone
go.drugbank.com/drugs/DB16165ApprovedInvestigationalFinerenone, or BAY 94-8862, is a mineralocorticoid receptor antagonist indicated to reduce the risk of sustained decline in glomerular filtration rate, end stage kidney disease, cardiovascular death, heart … [A236544] Spironolactone has low selectivity and affinity for the receptor; it dissociates quickly and can also have effects at the androgen, progesterone, and glucocorticoid receptors.
Categories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 SubstratesProducts: KERENDİA 10 MG FİLM KAPLI TABLET, 28 ADET, KERENDİA 10 MG FİLM KAPLI TABLET, 98 ADETFructose
go.drugbank.com/drugs/DB04173ApprovedInvestigationalMixtures: Formula EmCategories: Compounds used in a research, industrial, or household setting