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Displaying results 8391 - 8400 of 10000 in total
  1. Drug

    Zastumotide

    go.drugbank.com/drugs/DB14926
    Investigational

    It is under investigation in clinical trial NCT00257738 (0804 GCC: MAGE-A3/HPV 16 Vaccine for Squamous Cell Carcinoma of the Head and Neck). … Zastumotide is a recombinant MAGE-A3 Antigen-Specific Cancer Immunotherapeutic (MAGE-A3 ASCI) also known as astuprotimut-R.

  2. Drug

    Dabocemagene autoficel

    go.drugbank.com/drugs/DB17878
    Investigational

    Dabocemagene autoficel is an _ex vivo_, autologous cell-based gene therapy. It comprises autologous dermal fibroblasts genetically modified to express functional type VII collagen. … Developed by Castle Creek Biosciences Inc., dabocemagene autoficel is being investigated for the treatment of dystrophic epidermolysis bullosa.[L46797]

  3. Drug

    DYNE-251

    go.drugbank.com/drugs/DB18130
    Investigational

    It is being investigated for the treatment of Duchenne muscular dystrophy (DMD) in patients who are amenable to exon 51 skipping. … DYNE-251 is a phosphorodiamidate morpholino oligomer (PMO) conjugated to a fragment antibody (Fab) that binds to the transferrin receptor 1 (TfR1).

  4. Drug

    Pegapamodutide

    go.drugbank.com/drugs/DB14817
    Investigational

    Pegapamodutide is under investigation in clinical trial NCT02188303 (A Study of LY2944876 in Healthy Japanese and Non-Japanese Participants).

  5. Drug

    Icrucumab

    go.drugbank.com/drugs/DB14824
    Investigational

    Icrucumab is under investigation in clinical trial NCT01111604 (A Study of IMC-1121B or IMC-18F1 in Colorectal Cancer).

  6. Drug

    PF-5190457

    go.drugbank.com/drugs/DB14870
    Investigational

    PF-5190457 is under investigation in clinical trial NCT01522807 (A Study Of Three PF-05190457 Formulations In Healthy Volunteers).

  7. Drug

    Pimitespib

    go.drugbank.com/drugs/DB14876
    Investigational

    TAS-116 is under investigation in clinical trial NCT02965885 (A Study of TAS-116 in Patients With Solid Tumors).

  8. Drug

    PCO-371

    go.drugbank.com/drugs/DB14946
    Investigational

    PCO-371 is under investigation in clinical trial NCT02475616 (A Single Ascending Dose Study of PCO371 in Healthy Volunteers).

    Synonyms: non-peptide small molecule orally available agonist of the parathyroid hormone receptor type I, 2,4-IMIDAZOLIDINEDIONE, 1-(3,5-DIMETHYL-4-(2-((4-OXO-2-(4-(TRIFLUOROMETHOXY)PHENYL)-1,3,8-TRIAZASPIRO(4.5)DEC-1-EN-8-YL)SULFONYL)ETHYL)PHENYL)-5,5-DIMETHYL-
  9. Drug

    GI heptapeptide

    go.drugbank.com/drugs/DB15070
    Investigational

    GI heptapeptide is under investigation in clinical trial NCT01391208 (Esophageal Protocol for Detection of Neoplasia in the Digestive Tract).

  10. Drug

    ELX-02

    go.drugbank.com/drugs/DB15080
    Investigational

    ELX-02 is under investigation in clinical trial NCT03309605 (Phase 1 Study of ELX-02 in Healthy Adult Subjects).