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Bafilomycin A1
go.drugbank.com/drugs/DB06733ExperimentalThis is a useful tool as it can prevent the re-acidification of synaptic vesicles once they have undergone exocytosis.
NTx-265
go.drugbank.com/drugs/DB05649InvestigationalIt is also investigating use of the compound for neurodegenerative disorders, such as Huntington’s disease and Alzheimer’s disease.
FINLAY-FR-1
go.drugbank.com/drugs/DB16524ExperimentalFINLAY-FR-1, also known as Soberana 01, is a vaccine candidate for COVID-19 that is being led developmentally by the Finlay Vaccine Institute[L31373].
Diminazene
go.drugbank.com/drugs/DB03608ExperimentalDiminazene, also known as Diminazine, 4,4'-(Diazoamino)benzamidine, 4,4'-(1-triazene-1,3-diyl)bis-benzenecarboximidamide, diminazine aceturate, or Diminazene aceturate, is a trypanocidal agent.
MYR-101
go.drugbank.com/drugs/DB17075Investigational[L43567] The FDA has granted MYR-101 Fast Track, Rare Pediatric Disease (RPD), and Orphan Drug designations for the treatment of patients with Canavan disease.[L43572]
Distigmine
go.drugbank.com/drugs/DB13694InvestigationalDistigmine is available in several countries as a treatment of underactive detrusor and voiding dysfunction in the urinary tract where the active ingredient is distigmine bromide.
G17DT Immunogen
go.drugbank.com/drugs/DB04914InvestigationalIt is in phase III trials for advanced pancreatic cancer as a monotherapy and in combination with gemcitabine.
DDP733
go.drugbank.com/drugs/DB05049InvestigationalDDP733 is an oral prokinetic drug which Dynogen is developing as a treatment for both Irritable Bowel Syndrome with constipation (IBS-c) and nocturnal gastroesophageal reflux disease (NGERD).
Otelixizumab
go.drugbank.com/drugs/DB05496InvestigationalTolerx is developing otelixizumab to treat patients with type 1 diabetes, psoriasis and other autoimmune diseases such as rheumatoid arthritis.
DTS-201
go.drugbank.com/drugs/DB06071Experimentalsolid tumors, including tumors sensitive to doxorubicin and potentially other tumors which are not currently treated with doxorubicin but which express high levels of CD-10* or TOP** peptidases, such as