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Displaying results 8401 - 8410 of 10000 in total
  1. Drug

    RP-67580

    go.drugbank.com/drugs/DB16742
    Experimental

    Categories: Heterocyclic Compounds, 2-Ring, Neurokinin-1 Receptor Antagonists
  2. Drug

    Cytochalasin B

    go.drugbank.com/drugs/DB16766
    Experimental

    Synonyms: Cytochalasin B, Cytochalasin-BCategories: Heterocyclic Compounds, 2-Ring
  3. Drug

    Tyrphostin B56

    go.drugbank.com/drugs/DB16775
    Experimental

    Categories: Heterocyclic Compounds, 2-Ring
  4. Drug

    Adlinacogene civaparvovec

    go.drugbank.com/drugs/DB16788
    Investigational

    It uses proprietary zinc finger nuclease (ZFN) genome editing to insert into the DNA of liver cells a copy of the F9 gene, which controls the production of Factor IX. … [L46711] Developed by Sangamo Therapeutics Inc., it is being investigated for the treatment of hemophilia B.[L46706]

  5. Drug

    Lixmabegagene relduparvovec

    go.drugbank.com/drugs/DB16816
    Investigational

    Lixmabegagene relduparvovec, formerly known as LYS-GM101, is a recombinant adeno-associated virus vector serotype rh.10 (AAVrh.10) carrying the human β-galactosidase gene (GBL1).

  6. Drug

    LetibotulinumtoxinA

    go.drugbank.com/drugs/DB16820
    Approved

    [L42330] It is a 900 kDa multimeric complex comprising a 150 kDa toxin, a 130 kDa non-toxic non-haemagglutinating protein, and various other haemagglutinins. … [A249920] LetibotulinumtoxinA is a type A botulinum neurotoxin produced from fermentation of _Clostridium botulinum_ strain CBFC26.

    Synonyms: BoNT/A-DSCategories: Botulinum Toxins, Type A
  7. Drug

    AZD-5069

    go.drugbank.com/drugs/DB16822
    Investigational

    Categories: Heterocyclic Compounds, 1-Ring
  8. Drug

    Repotrectinib

    go.drugbank.com/drugs/DB16826
    ApprovedInvestigational

    Repotrectinib is a next-generation tyrosine kinase inhibitor (TKI) specifically designed to address resistance in the treatment of non-small cell lung cancer (NSCLC), specifically due to mutations in the … [A262056] Repotrectinib possesses a compact macrocyclic structure that both limits adverse interactions with resistance mutation hotspots and targets mutations in the solvent-front region.

    Synonyms: (3R,6S,)-45-FLUORO-3,6-DIMETHYL-5-OXA-2,8-DIAZA-1(5,3)-PYRAZOLO(1,5-A)PYRIMIDINA-4(1,2)-BENZENANONAPHAN-9-ONE, (7S,13R)-11-Fluoro-7,13-Dimethyl-6,7,13,14-Tetrahydro-1,15-Ethenopyrazolo[4,3-F][1,4,8,10]Benzoxatriazacyclotridecin-4(5H)-OneCategories: MATE 2 Inhibitors, P-glycoprotein inhibitors
  9. Drug

    AZD-7648

    go.drugbank.com/drugs/DB16834
    Investigational

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  10. Drug

    Pidnarulex

    go.drugbank.com/drugs/DB16846
    Investigational

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring