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Displaying results 8411 - 8420 of 10000 in total
  1. Drug

    Deoxyribonuclease I

    go.drugbank.com/drugs/DB16523
    Investigational

    Currently, DNase I is being investigated against respiratory failure in COVID-19 in the clinical trial NCT04541979 (Aerosoliserat DNase for Treatment of Respiratory Failure in Severe COVID-19). … It is normally found in saliva, urine, pancreatic secretions, and blood[A227723].

  2. Drug

    Abivertinib

    go.drugbank.com/drugs/DB15327
    Investigational

    The study is expected to be completed in March 2021.[L17398] … [L17383] It has been investigated for use in the treatment of non-small cell lung cancer (NSCLC) and B-cell malignancies.

  3. Drug

    Flizasertib

    go.drugbank.com/drugs/DB21613
    Investigational

    Flizasertib is under investigation in clinical trial NCT06602453 (A Study to Evaluate the Efficacy and Safety of GDC-8264 in Preventing Cardiac Surgery-Associated Acute Kidney Injury (AKI) and Major Adverse … The usage of the INN stem '-sertib' in the name indicates that Flizasertib is a serine/threonine kinase inhibitor.

  4. Drug

    Nicotinamide Mononucleotide

    go.drugbank.com/drugs/DB03227
    Investigational

    A nucleotide in which the nitrogenous base, nicotinamide, is in beta-N-glycosidic linkage with the C-1 position of D-ribose. Synonyms: Nicotinamide Ribonucleotide; NMN. [PubChem]

  5. Drug

    SS1(dsFv)-PE38

    go.drugbank.com/drugs/DB17579
    Investigational

    SS1(dsFv)-PE38 is under investigation in clinical trial NCT01051934 (A Phase I Trial of SS1 (Dsfv) PE38 With Paclitaxel, Carboplatin, and Bevacizumab in Subjects With Unresectable Non-small Cell Lung Adenocarcinoma

  6. Drug

    Irampanel

    go.drugbank.com/drugs/DB21123
    Investigational

    Irampanel is under investigation in clinical trial NCT02222961 (Single Increasing Dose Followed by Maintenance Dose Tolerance Study of BIIR 561 CL in Healthy Male Volunteers).

  7. Drug

    Aminorex

    go.drugbank.com/drugs/DB01490
    ExperimentalIllicit

    Aminorex is an amphetamine-like anorectic agent. It may cause pulmonary hypertension.

  8. Drug

    Gimatecan

    go.drugbank.com/drugs/DB06721
    Investigational

    Gimatecan is an orally available 7-t-butoxyiminomethyl-substituted lipophilic camptothecin derivative.

    Synonyms: (4S)-11-[(E)-(tert-butoxyimino)methyl]-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, (4S)-4-ethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1-H-pyrano[3',4':6,7]-indolizino-[1,2-b]-quinoline-11-carbaldehyde O-(tert-butyl)-(E)-oxime
  9. Drug

    Zoalene

    go.drugbank.com/drugs/DB11480
    ExperimentalVet approved

    Dinitolmide is a fodder additive for prophylaxis against coccidiosis infections in poultry.

  10. Drug

    Pridopidine

    go.drugbank.com/drugs/DB11947
    Investigational

    Pridopidine has been used in trials studying the treatment of Huntington's Disease.