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Displaying results 8411 - 8420 of 10000 in total
  1. Drug

    EGT-101

    go.drugbank.com/drugs/DB17645
    Experimental

    Developed by Esteve Pharmaceuticals, it is being investigated for Sanfilippo syndrome type A.[L45919] … EGT-101 is an adeno-associated viral vector serotype 9 (AAV9) vector-based gene therapy consisting of the human sulfamidase (SGSH) transgene.

  2. Drug

    NBF-006

    go.drugbank.com/drugs/DB21770
    Investigational

    This drug is a proprietary siRNA-based lyophilized lipid nanoparticle (LNP).[A273775, L52905] … NBF-006 is under investigation in clinical trial NCT03819387 (A Study of NBF-006 in Non-small Cell Lung, Pancreatic, or Colorectal Cancer).

  3. Drug

    Cintirorgon

    go.drugbank.com/drugs/DB20916
    Investigational

    Cintirorgon is a small molecule drug. Cintirorgon is under investigation in clinical trial NCT02929862 (Study of LYC-55716 in Adult Subjects With Locally Advanced or Metastatic Cancer).

  4. Drug

    Fosgonimeton

    go.drugbank.com/drugs/DB21516
    Investigational

    Fosgonimeton is a small molecule drug. Fosgonimeton is under investigation in clinical trial NCT05511558 (A Study of the Absorption, Metabolism, and Excretion of [14C]-Fosgonimeton (ATH-1017)).

  5. Drug

    CA-074 methyl ester

    go.drugbank.com/drugs/DB07223
    Experimental

    CA-074 methyl ester (CA-074Me) is a cell-permeable cathepsin B inhibitor. It is converted by cellular esterases to CA-074.[A258234,A258239]

    Synonyms: (S)-methyl 1-((2S,3S)-3-methyl-2-((2S,3S)-3-(propylcarbamoyl)oxirane-2-carboxamido)pentanoyl)pyrrolidine-2-carboxylate, Methyl (2S)-1-[(2S,3S)-3-methyl-2-[[(2S,3S)-3-(propylcarbamoyl)oxirane-2-carbonyl]amino]pentanoyl]pyrrolidine-2-carboxylate
  6. Drug

    Disitamab vedotin

    go.drugbank.com/drugs/DB17208
    Investigational

    Disitamab vedotin is an antibody-drug conjugate drug targeting human epidermal growth factor receptor 2 (HER2). It is currently being investigated for cancers.[A254721]

  7. Drug

    Ixmyelocel-T

    go.drugbank.com/drugs/DB17601
    Investigational

    Ixmyelocel-T is an expanded, autologous multicellular therapy cultured from bone-marrow mononuclear cells. Developed by Vericel Corporation, it is being investigated for cardiomyopathy.

  8. Drug

    Isospaglumic acid

    go.drugbank.com/drugs/DB19650
    Investigational

    Isospaglumic acid is a small molecule drug. … Isospaglumic acid is under investigation in clinical trial NCT06800274 (Clinical and Biological Evaluation of NAAGA Versus Azelastine Eye Drops in Allergic Subjects With Tear Film Dysfunction).

  9. Drug

    5-(5-(4-(4,5-dihydro-2-oxazoly)phenoxy)pentyl)-3-methyl osoxazole

    go.drugbank.com/drugs/DB08720
    Experimental

    This drug is known to target genome polyprotein. … 5-(5-(4-(4,5-dihydro-2-oxazoly)phenoxy)pentyl)-3-methyl osoxazole is a solid. This compound belongs to the phenol ethers.

  10. Drug

    Gavocabtagene autoleucel

    go.drugbank.com/drugs/DB17367
    Investigational

    which, upon expression, is incorporated into the endogenous T cell receptor (TCR) complex. … Gavocabtagene autoleucel is a novel cell therapy consisting of autologous genetically engineered T cells expressing a single-domain antibody that recognizes human Mesothelin, fused to the CD3-epsilon subunit