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Bexotegrast
go.drugbank.com/drugs/DB16515InvestigationalThe compound was granted orphan drug designation by the US FDA in August 2018 for treatment of IPF, and Pliant Therapeutics recently raised $100 million in Series C financing to support further clinical
Imidafenacin
go.drugbank.com/drugs/DB09262InvestigationalImidafenacin is an antispasmodic agent with anticholinergic effects. It antagonizes muscarinic receptors in the bladder to reduce the frequency of urination in the treatment of overactive bladder. It is marketed in Japan under the traden...
Distigmine
go.drugbank.com/drugs/DB13694InvestigationalDistigmine is available in several countries as a treatment of underactive detrusor and voiding dysfunction in the urinary tract where the active ingredient is distigmine bromide.
G17DT Immunogen
go.drugbank.com/drugs/DB04914InvestigationalIt is in phase III trials for advanced pancreatic cancer as a monotherapy and in combination with gemcitabine.
DDP733
go.drugbank.com/drugs/DB05049InvestigationalDDP733 is an oral prokinetic drug which Dynogen is developing as a treatment for both Irritable Bowel Syndrome with constipation (IBS-c) and nocturnal gastroesophageal reflux disease (NGERD).
Otelixizumab
go.drugbank.com/drugs/DB05496InvestigationalTolerx is developing otelixizumab to treat patients with type 1 diabetes, psoriasis and other autoimmune diseases such as rheumatoid arthritis.
Gam-COVID-Vac
go.drugbank.com/drugs/DB15848InvestigationalGam-COVID-Vac was created by Gamaleya Research Institute of Epidemiology and MIcrobiology in Russia.
Tesmilifene
go.drugbank.com/drugs/DB04905InvestigationalTesmilifene is a novel potentiator of chemotherapy which, when added to doxorubicin, achieved an unexpected and very large survival advantage over doxorubicin alone in a randomized trial in advanced breast cancer.
Horse chestnut
go.drugbank.com/drugs/DB13195InvestigationalHorse chestnut is a flowering plant commonly referred to as *Aesculus hippocastanum*.
Ellagic acid
go.drugbank.com/drugs/DB08846InvestigationalEllagic acid is present in several fruits such as cranberries, strawberries, raspberries, and pomegranates.