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Displaying results 8451 - 8460 of 10000 in total
  1. Drug

    QXL138AM

    go.drugbank.com/drugs/DB18552
    Investigational

    QXL138AM is a masked immunocytokine (MIC) comprised of an anti-CD138 immunoglobulin G1 antibody fused to interferon alpha 2a. It binds the CD138 protein on the surface of the tumour cells.

    Synonyms: Masked immunocytokine (MIC) comprised of an anti-CD138 immunoglobulin G1 antibody fused to interferon alpha 2a
  2. Drug

    Me-4(18F)DG

    go.drugbank.com/drugs/DB19207
    Investigational

    Me-4(18F)DG is under investigation in clinical trial NCT05558904 (An Investigational Scan (Me-4fdg PET/CT) for the Detection of Sodium-glucose Transport for Early Diagnosis of Lung Cancer).

    Synonyms: -methyl-4-(F-18)-fluoro-4-deoxy-d-glucopyranoside, Alpha-methyl-4-deoxy-4-((18)f)fluoro-d-glucopyranoside
  3. Drug

    CDX-301

    go.drugbank.com/drugs/DB19293
    Investigational

    CDX-301 is under investigation in clinical trial NCT02129075 (A Vaccine (CDX-1401) With or Without a Biologic Drug (CDX-301) for the Treatment of Patients With Stage IIB-IV Melanoma).

  4. Drug

    177Lu-PSMA-I&T

    go.drugbank.com/drugs/DB22176
    Investigational

    177Lu-PSMA-I&T is under investigation in clinical trial NCT04886986 (Phase I/II 225Ac-J591 Plus 177Lu-PSMA-I&T for Progressive Metastatic Castration Resistant Prostate Cancer).

    Synonyms: 177Lu-PSMA I&T, 177Lu-PSMA-I&T
  5. Drug

    AM103

    go.drugbank.com/drugs/DB05225
    Experimental

    AM103 is a novel inhibitor of 5-lipoxygenase-activiting protein (FLAP) that has demonstrated potential to treat asthma and cardiovascular disease by preventing the synthesis of LT, which triggers inflammation … It is being developed by Amira.

    Categories: Heterocyclic Compounds, 2-Ring
  6. Drug

    Carbomycin

    go.drugbank.com/drugs/DB11383
    ExperimentalVet approved

    The structure of carbomycin was generated in 1957 by Robert Woodward and later modified in 1965. … This antibacterial is obtained from _Streptomyces halstedii_ and it presents a large inhibitory effect against Gram-positive bacteria and some Mycoplasma strains.

    Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsSynonyms: Carbomycin A, Magnamycin A
  7. Drug

    Risvutatug rezetecan

    go.drugbank.com/drugs/DB23560
    Investigational

    It is under investigation in clinical trial NCT06885034 (A Study to Test the Safety and Effectiveness of GSK5764227, Alone or With Other Treatments, in Participants With Advanced Gastrointestinal Cancers … Risvutatug rezetecan (GSK5764227) is a novel investigational B7-H3-targeted antibody-drug conjugate.

  8. Drug

    Picafibrate

    go.drugbank.com/drugs/DB19574
    Experimental

    The usage of the INN stem '-fibrate' in the name indicates that Picafibrate is a clofibrate derivative, peroxisome proliferator activated receptor-a (PPAR-a) agonist. … Picafibrate is a small molecule drug.

    Categories: Heterocyclic Compounds, 1-Ring
  9. Drug

    Tiafibrate

    go.drugbank.com/drugs/DB19874
    Experimental

    The usage of the INN stem '-fibrate' in the name indicates that Tiafibrate is a clofibrate derivative, peroxisome proliferator activated receptor-a (PPAR-a) agonist. … Tiafibrate is a small molecule drug.

  10. Drug

    (S)-Warfarin

    go.drugbank.com/drugs/DB14055
    Investigational

    S-warfarin is 2-5 times more potent than the R-isomer in producing an anticoagulant response.[A7166] … Warfarin consists of a racemic mixture of two active enantiomers—R- and S- forms—each of which is cleared by different pathways.

    Categories: Vitamin K Antagonists, Cytochrome P-450 SubstratesSynonyms: (S)-4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone, 4-hydroxy-3-[(1S)-3-oxo-1-phenylbutyl]-2H-chromen-2-one