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Displaying results 8481 - 8490 of 10000 in total
  1. Drug

    BEA-17

    go.drugbank.com/drugs/DB18574
    Experimental

    BEA-17 is a small molecule targeted degrader of the epigenetic enzyme LSD1 and its co-factor CoREST.[L48330] It is under investigation for the treatment of glioblastoma.

  2. Drug

    Navtemadlin

    go.drugbank.com/drugs/DB15299
    Investigational

    Navtemadlin (AMG-232) is under investigation in clinical trial NCT03041688 (MDM2 Inhibitor AMG-232 and Decitabine in Treating Patients With Relapsed, Refractory, or Newly-Diagnosed Acute Myeloid Leukemia

  3. Drug

    IDM-1

    go.drugbank.com/drugs/DB05292
    Experimental

    It is comprised of MAK(Monocytes-derived Activated Killer) cells associated with MDX-210, a bispecific anti-HER-2/neu antibody developed by Medarex Inc.

  4. Drug

    Amperozide

    go.drugbank.com/drugs/DB08927
    Experimental

    It inhibits dopamine release and alters the firing of dopaminergic neurons. … Alternatively, amperozide's main use lies in veterinary medicine, where it is typically employed to minimize aggression and stress in intensively farmed pigs.

  5. Drug

    Flutrimazole

    go.drugbank.com/drugs/DB13425
    Investigational

    Flutrimazole is a topical imidazole antifungal agent with broad spectrum activity.

    Categories: Imidazole and Triazole Derivatives, Genito Urinary System and Sex Hormones
  6. Drug

    5-deoxyflavanone

    go.drugbank.com/drugs/DB03601
    Experimental

    These are compounds containing a flavan-3-one moiety, whose structure is characterized by a 2-phenyl-3,4-dihydro-2H-1-benzopyran bearing a ketone at the carbon C3.

  7. Drug

    Irampanel

    go.drugbank.com/drugs/DB21123
    Investigational

    Irampanel is under investigation in clinical trial NCT02222961 (Single Increasing Dose Followed by Maintenance Dose Tolerance Study of BIIR 561 CL in Healthy Male Volunteers).

  8. Drug

    Archexin

    go.drugbank.com/drugs/DB05971
    Investigational

    Categories: Nucleic Acids, Nucleotides, and Nucleosides
  9. Drug

    Quisovalimab

    go.drugbank.com/drugs/DB16482
    Investigational

    Categories: Amino Acids, Peptides, and Proteins
  10. Drug

    Pictilisib

    go.drugbank.com/drugs/DB11663
    Investigational

    Pictilisib has been used in trials studying the treatment of Solid Cancers, Breast Cancer, Advanced Solid Tumours, Metastatic Breast Cancer, and Non-Hodgkin's Lymphoma, Solid Cancers, among others.