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PMC-403
go.drugbank.com/drugs/DB18132InvestigationalPMC-403 is a novel Tie2-activating antibody being investigated for the treatment of systemic capillary leak syndrome.
Synonyms: a fully human monoclonal antibody that binds and activates the Tie2 receptorNGN-101
go.drugbank.com/drugs/DB18335InvestigationalNGN-101 is an adeno-associated virus serotype 9 vector with engineered transgene encoding the human CLN5 gene
AGTC-402
go.drugbank.com/drugs/DB18433InvestigationalAGTC-402 is a recombinant adeno-associated virus vector expressing the cyclic nucleotide gated channel alpha subunit (CNGA3).
Synonyms: rAAV2tYF-PR.1-hCNGA3ECT204
go.drugbank.com/drugs/DB18605InvestigationalECT204 is an autologous T-cell therapy whereby T cells are genetically modified to target tumor-specific antigens.
Prosetin
go.drugbank.com/drugs/DB18649InvestigationalProsetin is an orally administered blocker of MAP4K under investigation for the treatment of amyotrophic lateral sclerosis.[L48360]
Rovaleucel
go.drugbank.com/drugs/DB18691InvestigationalRovaleucel is an EBV-specific autologous T-cell therapy under investigation for the treatment of EBV-positive cancers.
RWJ-800088
go.drugbank.com/drugs/DB18693InvestigationalRWJ-800088 is a synthetic PEGylated thrombopoietin (TPO) mimetic (TPOm) peptide with no sequence homology to endogenous TPO.
Synonyms: a synthetic PEGylated thrombopoietin (TPO) mimetic (TPOm) peptide with no sequence homology to endogenous, METHOXYPOLYETHYLENEGLYCOL20000-PROPIONYL-L-ISOLEUCYL-L-GLUTAMYL-GLYCYL-L-PROLYL-L-THREONYL-L-LEUCYL-L-ARGINYL-L-GLUTAMINYL-L-2-NAPHTHYLALANYL-L-LEUCYL-L-ALANYL-L-ALANYL-L-ARGINYLSARCOSYL-NE-(METHOXYPOLYETHYLENEGLYCOL20000Brilacidin
go.drugbank.com/drugs/DB12997InvestigationalBrilacidin is under investigation for the supportive care of Mucositis, Stomatitis, Mouth Diseases, and Head and Neck Neoplasms.
Categories: Heterocyclic Compounds, 1-RingRavidasvir
go.drugbank.com/drugs/DB15652InvestigationalRavidasvir is under investigation in clinical trial NCT02961426 (Sofosbuvir Plus Ravidasvir for the Treatment of HCV Chronic Infection).
Categories: Heterocyclic Compounds, 2-RingLoteprednol
go.drugbank.com/drugs/DB00873ApprovedInvestigationalWithdrawnLoteprednol is a corticosteroid. A more commonly used formulation of loteprednol is its ester, [loteprednol etabonate].