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Displaying results 8531 - 8540 of 10000 in total
  1. Drug

    Adrenomedullin

    go.drugbank.com/drugs/DB19102
    Investigational

    Adrenomedullin is under investigation in clinical trial NCT06072118 (Adrenomedullin for CADASIL).

  2. Drug

    IL21120033

    go.drugbank.com/drugs/DB32508
    Experimental

    IL21120033 is a first-in-class, small-molecule selective CXCR7 agonist.

  3. Drug

    GLB-008

    go.drugbank.com/drugs/DB32800
    Experimental

    GLB-008 is a molecular glue degrader targeting VAV1.[L56125, L56126]

  4. Drug

    XM146-MPA-SN38

    go.drugbank.com/drugs/DB32865
    Experimental

    XM146-MPA-SN38 is a PDL1-targeting polypeptide-MPA-SN38 conjugate.

  5. Drug

    Deoxyribonuclease I

    go.drugbank.com/drugs/DB16523
    Investigational

    Deoxyribonuclease I (DNase I) is a human enzyme responsible for the digestion of extracellular DNA7[A227723]. It is normally found in saliva, urine, pancreatic secretions, and blood[A227723]. … Currently, DNase I is being investigated against respiratory failure in COVID-19 in the clinical trial NCT04541979 (Aerosoliserat DNase for Treatment of Respiratory Failure in Severe COVID-19).

  6. Drug

    MVA-SARS-2-S

    go.drugbank.com/drugs/DB16432
    Investigational

    MVA-SARS-2-S is a COVID-19 vaccine candidate that contains a Modified Vaccinia Virus Ankara (MVA) vector expressing the SARS-CoV-2 spike protein[L30453]. … MVA is a highly attenuated poxvirus vector[A226603] that has a high-level of biological safety due to its quality of being a non-replicating virus in mammalian hosts[L30458] and is used to develop vaccines

  7. Drug

    GLPG-1205

    go.drugbank.com/drugs/DB15346
    Investigational

    GLPG-1205 is under investigation in clinical trial NCT03725852 (A Clinical Study to Test How Effective and Safe GLPG1205 is for Patients With Idiopathic Pulmonary Fibrosis (IPF)).

  8. Drug

    Reloxiliase

    go.drugbank.com/drugs/DB17653
    Experimental

    Reloxiliase is a first-in-class, oral crystalline formulation of the oxalate-specific, microbial enzyme oxalate decarboxylase. It is being investigated for the treatment of hyperoxaluria.[A258823]

  9. Drug

    WP-1301

    go.drugbank.com/drugs/DB17702
    Experimental

    WP1301 is a synthetic peptide derived from hFVIII. It binds to an MHC class II molecule and is recognized by a Factor VIII-specific T cell.[L46138]

  10. Drug

    AGA2115

    go.drugbank.com/drugs/DB17840
    Investigational

    AGA2115 is a humanized bispecific antibody neutralizing both sclerostin and Dickkopf-1. … Developed by Angitia Biopharmaceuticals, AGA2115 is being investigated for the treatment of osteogenesis imperfect.[L46646]