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Displaying results 8561 - 8570 of 10000 in total
  1. Drug

    Daniquidone

    go.drugbank.com/drugs/DB12804
    Investigational

    Daniquidone has been used in trials studying the treatment of Neoplasms.

    Categories: Heterocyclic Compounds, 2-Ring
  2. Drug

    Zoliflodacin

    go.drugbank.com/drugs/DB12817
    ApprovedInvestigational

    [A274938,L54748] It is indicated as a single-dose oral therapy for the treatment of uncomplicated urogenital gonorrhea. … [A275268] Zoliflodacin is a first-in-class spiropyrimidinetrione antibiotic designed to address this need by inhibiting bacterial type II topoisomerases (DNA gyrase and topoisomerase IV), thereby blocking

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates
  3. Drug

    Concizumab

    go.drugbank.com/drugs/DB12820
    ApprovedInvestigational

    Concizumab is a humanized IgG4 monoclonal antibody targeting the Kunitz-2 domain of tissue factor pathway inhibitor (TFPI), a key regulator of the coagulation cascade. … [L52043] Concizumab-mtci (Alhemo) was approved by the FDA in December 2024 for use in patients with hemophilia A or B with inhibitors.

  4. Drug

    Gabexate

    go.drugbank.com/drugs/DB12831
    Investigational

    Gabexate is a synthetic serine protease inhibitor which has been used as an anticoagulant. It also known to decrease production of inflammatory cytokines.

  5. Drug

    Grapiprant

    go.drugbank.com/drugs/DB12836
    InvestigationalVet approved

    Grapiprant, also known as AT-001 and CJ-023, is a drug from the piprant class. … These molecules were derived from acylsulfonamide and are characterized to be a novel series of para-N-acylaminomethylbenzoic acid known to be prostaglandin receptor antagonists.

    Categories: P-glycoprotein substrates, Heterocyclic Compounds, 1-Ring
  6. Drug

    Glial growth factor 2

    go.drugbank.com/drugs/DB12841
    Investigational

    Glial growth factor 2 has been used in trials studying the treatment of Heart Failure.

    Synonyms: Glial growth factor 2
  7. Drug

    Pegamotecan

    go.drugbank.com/drugs/DB12842
    Investigational

    Pegamotecan has been used in trials studying the treatment of Cancer of Stomach, Sarcoma, Soft Tissue, and Gastroesophageal Cancer.

    Categories: Compounds used in a research, industrial, or household setting
  8. Drug

    DA-6886

    go.drugbank.com/drugs/DB12853
    Investigational

    DA-6886 has been used in trials studying the treatment of Irritable Bowel Syndrome.

    Categories: Heterocyclic Compounds, 1-Ring
  9. Drug

    Apricitabine

    go.drugbank.com/drugs/DB12855
    Investigational

    Apricitabine has been used in trials studying the treatment of HIV Infections.

    Categories: Heterocyclic Compounds, 1-Ring
  10. Drug

    GS-9256

    go.drugbank.com/drugs/DB12876
    Investigational

    GS-9256 has been used in trials studying the treatment of HCV Infection and Chronic Hepatitis C Infection.