Apricitabine

DB12855InvestigationalSmall molecule

Apricitabine has been used in trials studying the treatment of HIV Infections.

Mechanism: Apricitabine is a type of medicine called a nucleoside reverse transcriptase inhibitor (NRTI). NRTIs work by blocking reverse transcriptase, a protein that HIV needs to make more copies of itself.
Curator reviewed
Formula / weight: C₈H₁₁N₃O₃S · 229.25 g/mol (avg)
Code names: AVX-754 · BCH 10618 · SPD 754

Resolves to

Compound

Structure

InChIKeyRYMCFYKJDVMSIR-RNFRBKRXSA-NSMILESNC1=NC(=O)N(C=C1)[C@H]1CO[C@@H](CO)S1

Targets

What you can answer from here — as of June 15, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

4Clinical trialsPhase, status and sponsor resolved per trial

5+ReferencesStructured and connected to the statements they support

Which drugs share a target with Apricitabine, and which of those have an active Phase 3 trial?

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