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Levodopa

The first developed drug product that was approved by the FDA was a levodopa and carbidopa combined product called Sinemet that was approved on May 2, 1975[A177781,L6133]. … Levodopa can be metabolised to dopamine on either side of the blood-brain barrier and so it is generally administered with a dopa decarboxylase inhibitor like carbidopa to prevent metabolism until after it has

Witch hazel

Cefotaxime

Like other third-generation cephalosporins, it has broad spectrum activity against Gram positive and Gram negative bacteria.

Betamethasone

[A192444] Betamethasone has potent glucocorticoid activity and negligible mineralocorticoid activity.[A192444] … [A192444] It can be used topically to manage inflammatory skin conditions such as eczema, and parenterally to manage several disease states including autoimmune disorders.

Erdosteine

Erdosteine has been shown to be safe and well tolerated in clinical trials. … Erdosteine is a drug that causes a breakdown of mucus, also known as a _mucolytic_ agent.

Afamelanotide

[L9092] Despite its relatively recent approval, afamelanotide has been available for use as an orphan drug in both the US and EU since 2008.[L9122,L9125]

Duloxetine

[label] It was originally discovered in 1993 and developed by Eli Lilly and Company as LY248686. … [A178741] Duloxetine first received approval from the FDA in August, 2004 as Cymbalta for the treatment of Major Depressive Disorder.

Paeonia lactiflora root

Lipotecan