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Displaying results 8591 - 8600 of 10000 in total
  1. Drug

    IK-930

    go.drugbank.com/drugs/DB18149
    Investigational

    IK-930 is an oral, paralog-selective TEAD inhibitor.

  2. Drug

    Efocipegtrutide

    go.drugbank.com/drugs/DB18194
    Investigational

    Efocipegtrutide is a long-acting, monomeric peptide triple agonist.

    Synonyms: IMMUNOGLOBULIN G4 (HUMAN .GAMMA.4-CHAIN C REGION C-TERMINAL FRAGMENT), DIMER, 1-(1-(3-HYDROXYPROPYL)-L-PROLINE), 1-ETHER WITH .ALPHA.-(3-((3-(3-MERCAPTO-2,5-DIOXO-1-PYRROLIDINYL)-1-OXOPROPYL)AMINO)PROPYL, HM15211 (LONG-ACTING GLP-1/GIP/GLUCAGON TRIPLE AGONIST)
  3. Drug

    PT217

    go.drugbank.com/drugs/DB18472
    Investigational

    PT217 is a bispecific Antibody against DLL3 and CD47

  4. Drug

    Ceftiofur

    go.drugbank.com/drugs/DB11485
    ExperimentalVet approved

    Ceftiofur is a third generation cephalosporin antibiotic, first described in 1987, and now used in veterinary medicine. … It is resistant to hydrolysis by beta-lactamase, and has activity against both Gram-positive and Gram-negative bacteria. E. coli strains resistant to ceftiofur have been reported.

    Categories: Heterocyclic Compounds, 2-Ring
  5. Drug

    Brifentanil

    go.drugbank.com/drugs/DB09172
    ExperimentalIllicit

    Brifentanil (also known as A-3331) is an analog of fentanyl, a potent opioid. This drug is classified as an opioid analgesic and was developed in the early 1990s.

    Categories: Heterocyclic Compounds, 1-Ring
  6. Drug

    ND1251

    go.drugbank.com/drugs/DB05132
    Experimental

    ND1251 is a very potent compound with a large safety margin. … ND1251 is an orally active phosphodiesterase-4 (PDE4) inhibitor, a mechanism clinically proven to play a role in alleviating symptoms of depression.

  7. Drug

    EPC2407

    go.drugbank.com/drugs/DB05189
    Investigational

    EPC2407 is a novel small molecule vascular disruption agent and apoptosis inducer for the treatment of patients with advanced solid tumors and lymphomas. … It is intended for the treatment of advanced cancer patients with solid tumors that are well vascularized.

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  8. Drug

    Anti-SARS-CoV-2 equine immunoglobulin fragments

    go.drugbank.com/drugs/DB16368
    Investigational

    [L27796] INOSARS is composed of F(ab’)2 fragments extracted from hyperimmune equine serum. … Anti-SARS-CoV-2 equine immunoglobulin fragments, also known as INOSARS, is a polyvalent passive immunization being tested in the clinical trial NCT04514302 (Safety and Efficacy of Anti-SARS-CoV-2 Equine

    Synonyms: Anti-SARS-CoV-2 equine immunoglobulin fragments F(ab')2
  9. Drug

    DCLL-9718S

    go.drugbank.com/drugs/DB17392
    Investigational

    DCLL9718S is an antibody-drug conjugate targeting C-type lectin-like molecule-1 (CLL-1). … DCLL9718S is under investigation in clinical trial NCT03298516 (A Study of DCLL9718S in Participants With Relapsed or Refractory Acute Myeloid Leukemia (AML) or DCLL9718S in Combination With Azacitidine

    Synonyms: THIOMAB antibody drug conjugate comprised of humanized IgG1 anti-C-type lectin-like molecule-1 monoclonal antibody and DNA alkylating cross-linking agent pyrrolo [2,1-c][1,4] benzodiazepine dimer
  10. Drug

    Polyvalent antigen-KLH conjugate vaccine

    go.drugbank.com/drugs/DB17565
    Investigational

    Polyvalent antigen-KLH conjugate vaccine is a multivalent cancer vaccine comprised of the five tumor-associated antigens (TAAs) globo H, GM2 ganglioside, Tn-MUC1, TF, and sTn conjugated with the immunoadjuvant … It is under investigation in clinical trial NCT01223235 (Polyvalent Vaccine-klh Conjugate + Opt-821 Given in Combination With Bevacizumab).