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Displaying results 8631 - 8640 of 10000 in total
  1. Drug

    Ibrigampar

    go.drugbank.com/drugs/DB05490
    Investigational

    T131 is a selective modulator of PPARg (peroxisome proliferator activated receptor gamma), a receptor involved in regulating the body’s ability to respond to insulin.

    Categories: Heterocyclic Compounds, 2-Ring
  2. Drug

    ATN-161

    go.drugbank.com/drugs/DB05491
    Investigational

    ATN-161 is a non-RGD based integrin binding peptide targeting alpha-5 beta-1 and alpha-v beta-3. … expected to extend to a variety of cancers.

  3. Drug

    Elacytarabine

    go.drugbank.com/drugs/DB05494
    Investigational

    Elacytarabine is a fatty acid derivative of [cytarabine], an approved cytotoxic cancer drug. Cytarabine has limitations such as minimal uptake in solid tumours and is only used to treat leukaemia. … Elacytarabine is a patented new chemical entity of the nucleoside analog class, with improved biological properties and the potential to treat solid tumours such as non-small cell lung cancer, malignant

    Categories: Heterocyclic Compounds, 1-Ring
  4. Drug

    TAK-428

    go.drugbank.com/drugs/DB05499
    Experimental

    TAK-428 is a drug for treating diabetic neuropathy.

  5. Drug

    LI-301

    go.drugbank.com/drugs/DB05509
    Experimental

    It has a novel mode of action combining both the light effect of a Selective Serotonin Reuptake Inhibitor ("SSRI")(most likely antagonistic at 5HT1a receptors) and antagonism at mu-opioid receptors. … LI 301 is an orally bio-available compound delivered in a fast melt mechanism with taste masking enabling it to be taken anytime without water.

  6. Drug

    PI-0824

    go.drugbank.com/drugs/DB05516
    Investigational

    Peptimmune, Inc. has developed a new therapy for the treatment of PV, PI-0824.

  7. Drug

    CPG 10101

    go.drugbank.com/drugs/DB05530
    Investigational

    It is a toll-like receptor 9 (TLR9) agonist with antiviral and immunomodulatory properties that could potentially influence chronic infection with HCV. … CPG 10101 is a synthetic oligodeoxynucleotide (ODN) in clinical trials.

  8. Drug

    alpha-Pyrrolidinononanophenone

    go.drugbank.com/drugs/DB05531
    Investigational

    Categories: Heterocyclic Compounds, 1-Ring
  9. Drug

    BMS-488043

    go.drugbank.com/drugs/DB05532
    Experimental

    BMS-488043 has been investigated as an anti-HIV agent.

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  10. Drug

    Ostabolin-C

    go.drugbank.com/drugs/DB05536
    Investigational

    Ostabolin C was under investigation in clinical trial NCT00787358 (A Proof-of-Concept Study Investigating the Safety and Efficacy of ZT-031 on Hip Fracture Healing in Men and Postmenopausal Women (SHIFT

    Synonyms: -GLUTAMYL-L-ISOLEUCYL-L-GLUTAMINYL-L-LEUCYL-L-METHIONYL-L-HISTIDYL-L-ASPARAGINYL-L-LEUCYLGLYCYL-L-LYSYL-L-HISTIDYL-L-LEUCYL-L-ASPARAGINYL-L-SERYL-L-METHIONYL-L-.ALPHA., L-VALINAMIDE, L-SERYL-L-VALYL-L-SERYL-L-.ALPHA.