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Bisoctrizole
go.drugbank.com/drugs/DB11262ApprovedIt is a benzotriazole-based organic compound that absorbs, reflects, and scatters both UV-A and UV-B rays. … Bisoctrizole, or methylene bis-benzotriazolyl tetramethylbutylphenol, is a broad-spectrum organic UV filter that is marketed as Tinosorb M [A19212].
Dihydro-alpha-ergocryptine
go.drugbank.com/drugs/DB11274ApprovedThese two compounds are differentiated in the position of a methyl group. This structural difference is due to a proteinogenic amino acid replacement from leucine to isoleucine. … Alpha-dihydroergocryptine approved drug product is as a part of an ergoloid mixture. To know more about this mixture, please visit [DB01049]
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: α-dihydroergocryptine, dihydro-α-ergocryptineAlectinib
go.drugbank.com/drugs/DB11363ApprovedInvestigationalAlectinib is a second generation oral drug that selectively inhibits the activity of anaplastic lymphoma kinase (ALK) tyrosine kinase. … It is specifically used in the treatment of non-small cell lung cancer (NSCLC) expressing the ALK-EML4 (echinoderm microtubule-associated protein-like 4) fusion protein that causes proliferation of NSCLC
Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, P-glycoprotein inhibitorsSynonyms: 9-ethyl-6,6-dimethyl-8-[4-(morpholin-4-yl)piperidin-1-yl]-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrileMaropitant
go.drugbank.com/drugs/DB11427ExperimentalVet approvedMaropitant, used as maropitant citrate, is a neurokinin receptor antagonist, which was developed by Zoetis specifically for the treatment of motion sickness and vomiting in dogs.
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesOclacitinib
go.drugbank.com/drugs/DB11441ExperimentalVet approvedCategories: Heterocyclic Compounds, 1-Ring, Janus Kinase 1, antagonists & inhibitorsBunamidine
go.drugbank.com/drugs/DB11501ExperimentalVet approvedBunamidine is a veterinary anti-platyhelmintic agent used for taenia infestations.
Synonyms: N,N-Dibutyl-4-(hexyloxy)-1-naphthamidine, N,N-Dibutyl-4-hexyloxy-1-naphthamidinCefovecin
go.drugbank.com/drugs/DB11505ExperimentalVet approvedCefovecin is a cephalosporin antibiotic used for the treatment of skin infections in cats and dogs. … It is used for the treatment of skin infections caused by Pasturella multocida in cats, and Staphylococcus intermedius/S. canis in dogs.
Categories: Heterocyclic Compounds, 2-RingZolazepam
go.drugbank.com/drugs/DB11555ExperimentalVet approvedZolazepam is a pyrazolodiazepinone derivative used as an anaesthetic in veterinary medicine.
Categories: Heterocyclic Compounds, 2-RingAluminum chlorohydrate
go.drugbank.com/drugs/DB11573ApprovedAluminum chlorohydrate is a group of water-soluble aluminum complexes with the general formula AlnCl(3n-m)(OH)m. … It is also used as a coagulant in the water purification process.
Mixtures: KURSEPT %19 + %1 KREM (30 G), PERS-MANT %19 + %2 JEL (30 G)Products: 5 Day, A BilleGrazoprevir
go.drugbank.com/drugs/DB11575ApprovedGrazoprevir is an inhibitor of NS3/4A, a serine protease enzyme, encoded by HCV genotypes 1 and 4 [synthesis]. … in combination with [DB11574] for genotypes 1a, 1b, and 4 of Hepatitis C [A19593].
Mixtures: ZEPATIER® TABLETAS RECUBIERTASCategories: P-glycoprotein substrates, Cytochrome P-450 Substrates