Search
Tadalafil
go.drugbank.com/drugs/DB00820ApprovedInvestigationalTadalafil is a selective phosphodiesterase-5 inhibitor that is used in the treatment of erectile dysfunction (ED), pulmonary arterial hypertension (PAH), and benign prostatic hypertrophy. … In contrast to other PDE5 inhibitors like [sildenafil], tadalafil has greater selectivity for PDE5 and a longer half-life which has made it a more suitable option for chronic once-daily dosing in the treatment
Mixtures: TADA PLUS 30/20 MG FILM KAPLI TABLET ,4 ADET, TADA PLUS 30/20 MG FILM KAPLI TABLET ,8 ADETCategories: 5-alpha Reductase Inhibitors, Cytochrome P-450 SubstratesPhenmetrazine
go.drugbank.com/drugs/DB00830ApprovedIllicitA sympathomimetic drug used primarily as an appetite depressant. Its actions and mechanisms are similar to dextroamphetamine.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 2-phenyl-3-methylmorpholinePhensuximide
go.drugbank.com/drugs/DB00832ApprovedPhensuximide is a member of the succinimide class with anticonvulsant properties. … The frequency of attacks is reduced by depression of nerve transmission in the motor cortex.
Categories: Heterocyclic Compounds, 1-RingProgabide
go.drugbank.com/drugs/DB00837ExperimentalProgabide is an analog and prodrug of gamma-aminobutyric acid. It is commonly used in the treatment of epilepsy. It has agonistic activity for both the GABAA and GABAB receptors. … In clinical trials, progabide has been investigated for Parkinson's disease, schizophrenia, clinical depression and anxiety disorder; its therapeutic effectiveness in these conditions is not fully elucidated
Clocortolone
go.drugbank.com/drugs/DB00838ApprovedClocortolone is a medium potency corticosteroid that is often used as a topical cream for the relief of inflammatory oand pruritic (itching) arising from steroid-responsive dermatoses of the scalp.
Synonyms: 9-chloro-6alpha-Fluoro-11beta,21-dihydroxy-16alpha-methyl-1,4-pregnadien-3,20-dione, 9-chloro-6alpha-Fluoro-16alpha-methyl-1,4-pregnadiene-11beta,21-diol-3,20-dioneTolazamide
go.drugbank.com/drugs/DB00839ApprovedA sulphonylurea hypoglycemic agent with actions and uses similar to those of chlorpropamide.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesSynonyms: 1-(Hexahydro-1-azepinyl)-3-p-tolylsulfonylurea, 1-(Hexahydro-1H-azepin-1-yl)-3-(p-tolylsulfonyl)ureaOxazepam
go.drugbank.com/drugs/DB00842Approvedas compared to other benzodiazepines, and is likely owing in part to oxazepam's relatively simple metabolism. … Oxazepam is an intermediate-acting, 3-hydroxybenzodiazepine used in the treatment of alcohol withdrawal and anxiety disorders.
Categories: Heterocyclic Compounds, 2-RingSynonyms: (RS)-OxazepamDonepezil
go.drugbank.com/drugs/DB00843ApprovedInvestigational[A182411] Donepezil, also known as Aricept, is a piperidine derivative acetylcholinesterase inhibitor used in the management of the dementia of Alzheimer's Disease, and in some cases, is used to manage … In 2016, the global burden of dementia was estimated to be 43.8 million, demonstrating a significant increase from a global prevalence of 20.2 million in 1990.
Mixtures: DOMINGO 5/5/80 MG EFERVESAN TABLET, 30 ADET, DOMINGO 5/5/80 MG EFERVESAN TABLET, 90 ADETCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingCysteamine
go.drugbank.com/drugs/DB00847ApprovedInvestigationalCystinosis is a rare disease caused by mutations in the CTNS gene that encodes for cystinosin, a protein responsible for transporting cystine out of the cell lysosome. … A defect in cystinosin function is followed by cystine accumulation throughout the body, especially the eyes and kidneys.
Synonyms: 2-amino-1-ethanethiol, β-MEAProducts: CYSTAGON ® 150 MG, CYSTAGON ® 50 MG CAPSULASPerphenazine
go.drugbank.com/drugs/DB00850ApprovedInvestigationalAn antipsychotic phenothiazine derivative with actions and uses similar to those of chlorpromazine.
Mixtures: โพลีบอน 4-10, Etrafon 2 10Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates