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Halofuginone
go.drugbank.com/drugs/DB04866InvestigationalVet approvedFood and Drug Administration in March, 2000. … Halofuginone also effectively suppresses tumor progression and metastasis in mice.
(1H-indol-3-yl)-(2-mercapto-ethoxyimino)-acetic acid
go.drugbank.com/drugs/DB03455ExperimentalThese are compounds containing an acetic acid (or a derivative) linked to the C3 carbon atom of an indole. (1H-indol-3-yl)-(2-mercapto-ethoxyimino)-acetic acid is known to target interleukin-2.
N-(carboxycarbonyl)-D-phenylalanine
go.drugbank.com/drugs/DB08263ExperimentalN-(carboxycarbonyl)-D-phenylalanine is a solid. This compound belongs to the n-acyl-alpha amino acids. … These are compounds containing an alpha amino acid which bears an acyl group at its terminal nitrogen atom. It targets the protein hypoxia-inducible factor 1-alpha inhibitor.
Synonyms: N-(carboxycarbonyl)-D-phenylalaninePamufetinib
go.drugbank.com/drugs/DB20752InvestigationalThe usage of the INN stem '-tinib' in the name indicates that Pamufetinib is a tyrosine kinase inhibitor. Pamufetinib is under investigation in clinical trial NCT04999761 (AB122 Platform Study).
Renzapride
go.drugbank.com/drugs/DB04917InvestigationalIt has been suggested that renzapride is effective in the treatment of irritable bowel syndrome with alternating stool pattern. It is being developed by Alizyme of the UK. … Renzapride is currently in Phase III clinical development in the United States for the treatment of constipation-predominant irritable bowel syndrome (IBS-C).
Decoquinate
go.drugbank.com/drugs/DB11394ExperimentalVet approvedDecoquinate is used in veterinary to delay the growth and reproduction of coccidian parasites.
Bersanlimab
go.drugbank.com/drugs/DB17377InvestigationalBersanlimab is an investigational monoclonal antibody directed against intercellular adhesion molecule 1 (ICAM-1).
AQ-13
go.drugbank.com/drugs/DB17749InvestigationalAQ-13 is an 4-aminoquinoline analog being investigated for the treatment of malaria.
Synonyms: 1,3-propanediamine, n'-(7-chloro-4-quinolinyl)-n,n-diethyl-, dihydrochlorideEA-2353
go.drugbank.com/drugs/DB18506InvestigationalEA-2353 is a small molecule inhibitor of kinase mediators of the Wnt pathway.
Tenalisib
go.drugbank.com/drugs/DB15295InvestigationalTenalisib is under investigation in clinical trial NCT03711604 (Compassionate Use Study of Tenalisib (RP6530)).