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Displaying results 8661 - 8670 of 10000 in total
  1. Drug

    Socazolimab

    go.drugbank.com/drugs/DB18845
    Investigational

    Socazolimab is under investigation in clinical trial NCT04878016 (A Study of Carboplatin Plus Etoposide With or Without ZKAB001 (Anti-pd-l1 Antibody) in Patients With ES-SCLC).

    Synonyms: Immunoglobulin g1, anti-(human programmed death-ligand 1) (human monoclonal zkab001 .gamma.1-chain), disulfide with human monoclonal zkab001 .lambda.-chain, dimer
  2. Drug

    Depemokimab

    go.drugbank.com/drugs/DB18846
    ApprovedInvestigational

    Depemokimab is a humanized Immunoglobulin G1 (IgG1) monoclonal antibody and a long-acting drug. … [A275338] Depemokimab blocks interleukin-5 (IL-5), a key cytokine that regulates eosinophil maturation, survival, and recruitment.

    Categories: Interleukin-5 AntagonistSynonyms: Immunoglobulin g1, anti-(human interleukin 5) (human-mus musculus monoclonal gsk3511294 .gamma.1-chain), disulfide with human-mus musculus monoclonal gsk3511294 .kappa.-chain, dimer
  3. Drug

    Deuruxolitinib

    go.drugbank.com/drugs/DB18847
    ApprovedInvestigational

    Deuruxolitinib is a deuterated form of [ruxolitinib] that selectively inhibits Janus kinases (JAK) JAK1 and JAK2. … [L51083] Alopecia areata is an autoimmune condition that attacks the hair follicles and leads to unpredictable hair loss in the scalp and other areas of the body.

    Categories: MATE 2 Inhibitors, P-glycoprotein substratesSynonyms: (3r)-3-(2,2,3,3,4,4,5,5-d8)cyclopentyl-3-(4-(7h-pyrrolo(2,3-d)pyrimidin-4-yl)-1h-pyrazol-1-yl)propanenitrile, 1h-pyrazole-1-propanenitrile, .beta.-(cyclopentyl-2,2,3,3,4,4,5,5-d8)-4-(7h-pyrrolo(2,3-d)pyrimidin-4-yl)-, (.beta.r)-
  4. Drug

    Rosnilimab

    go.drugbank.com/drugs/DB18851
    Investigational

    Rosnilimab is under investigation in clinical trial NCT06041269 (A Study of Efficacy and Safety of Rosnilimab in Subjects With Moderate to Severe Rheumatoid Arthritis (RENOIR)).

    Synonyms: Immunoglobulin g1, anti-(human programmed cell death protein 1) (human-mus musculus monoclonal anb030 .gamma.1-chain), disulfide with human-mus musculus monoclonal anb030 .kappa.-chain, dimer
  5. Drug

    Nofazinlimab

    go.drugbank.com/drugs/DB18852
    Investigational

    Nofazinlimab is under investigation in clinical trial NCT04194775 (A Study of Nofazinlimab (CS1003) in Subjects With Advanced Hepatocellular Carcinoma).

    Synonyms: Recombinant pd-1 mab cs1003, Immunoglobulin g4 (223-proline), anti-(human programmed cell death protein 1) (human-mus musculus monoclonal cs1003 .gamma.4-chain), disulfide with human-mus musculus monoclonal cs1003 .kappa.
  6. Drug

    Ragifilimab

    go.drugbank.com/drugs/DB18853
    Investigational

    Ragifilimab is under investigation in clinical trial NCT04225039 (Anti-gitr/anti-pd1/stereotactic Radiosurgery, in Recurrent Glioblastoma).

    Synonyms: Immunoglobulin g1 (de-448-lysine), anti-(human tumor necrosis factor receptor tnfrsf18) (human-mus musculus monoclonal incagn01876.gamma.1-chain), disulfide with human-mus musculus monoclonal incagn01876
  7. Drug

    Etigilimab

    go.drugbank.com/drugs/DB18854
    Investigational

    Etigilimab is under investigation in clinical trial NCT04761198 (A Study of Etigilimab and Nivolumab in Subjects With Locally Advanced or Metastatic Tumors.).

    Synonyms: Immunoglobulin g1, anti-(human receptor tigit(t-cell immunoreceptor with ig and itim domains)) (humanized mouse monoclonal omp-313m32 .gamma.1-chain), disulfide with humanized mouse monoclonal omp-313m32
  8. Drug

    Povorcitinib

    go.drugbank.com/drugs/DB18855
    Investigational

    Povorcitinib is under investigation in clinical trial NCT06113445 (A Study to Evaluate Efficacy and Safety of Povorcitinib in Participants With Nonsegmental Vitiligo (STOP-V1)).

  9. Drug

    Gatipotuzumab

    go.drugbank.com/drugs/DB18861
    Investigational

    Gatipotuzumab is under investigation in clinical trial NCT01899599 (Pankomab-gex™ Versus Placebo as Maintenance Therapy in Advanced Ovarian Cancer).

  10. Drug

    Giloralimab

    go.drugbank.com/drugs/DB18862
    Investigational

    Giloralimab is under investigation in clinical trial NCT04807972 (Study to Evaluate Adverse Events and Change in Disease Activity When Intravenous (IV) Infusion of ABBV-927 Is Administered in Combination

    Synonyms: Immunoglobulin g1, anti-(human cd40 antigen) (human-mus musculus monoclonal pr-1614645 .gamma.1-chain), disulfide with human-mus musculus monoclonal pr-1614645 .kappa.-chain, dimer