Deuruxolitinib
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This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Explore a selection of our essential drug information below, or:
Identification
- Generic Name
- Deuruxolitinib
- DrugBank Accession Number
- DB18847
- Background
Deuruxolitinib is under investigation in clinical trial NCT03898479 (Extension Study to Evaluate Safety and Efficacy of CTP-543 in Adults With Alopecia Areata).
- Type
- Small Molecule
- Groups
- Investigational
- Structure
- Weight
- Average: 314.422
Monoisotopic: 314.209508571 - Chemical Formula
- C17H18N6
- Synonyms
- (3r)-3-(2,2,3,3,4,4,5,5-d8)cyclopentyl-3-(4-(7h-pyrrolo(2,3-d)pyrimidin-4-yl)-1h-pyrazol-1-yl)propanenitrile
- 1h-pyrazole-1-propanenitrile, .beta.-(cyclopentyl-2,2,3,3,4,4,5,5-d8)-4-(7h-pyrrolo(2,3-d)pyrimidin-4-yl)-, (.beta.r)-
- D8-ruxolitinib
- External IDs
- C-21543
- CTP-543
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
- Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.
- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Categories
- Drug Categories
- Not Available
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 0CA0VSF91Y
- CAS number
- 1513883-39-0
- InChI Key
- HFNKQEVNSGCOJV-FBXGHSCESA-N
- InChI
- InChI=1S/C17H18N6/c18-7-5-15(12-3-1-2-4-12)23-10-13(9-22-23)16-14-6-8-19-17(14)21-11-20-16/h6,8-12,15H,1-5H2,(H,19,20,21)/t15-/m1/s1/i1D2,2D2,3D2,4D2
- IUPAC Name
- SMILES
- [2H]C1([2H])C([C@@H](CC#N)N2C=C(C=N2)C2=C3C=CNC3=NC=N2)C([2H])([2H])C([2H])([2H])C1([2H])[2H]
References
- General References
- Not Available
- External Links
- ChemSpider
- 115010950
- ChEMBL
- CHEMBL4594381
- Wikipedia
- Deuruxolitinib
Clinical Trials
- Clinical Trials
Clinical Trial & Rare Diseases Add-on Data Package
Explore 4,000+ rare diseases, orphan drugs & condition pairs, clinical trial why stopped data, & more. Preview package Phase Status Purpose Conditions Count Start Date Why Stopped 100+ additional columns Unlock 175K+ rows when you subscribe.View sample data3 Active Not Recruiting Treatment Alopecia Areata (AA) 1 somestatus stop reason just information to hide 3 Completed Treatment Alopecia Areata (AA) 2 somestatus stop reason just information to hide 2 Completed Treatment Alopecia Areata (AA) 4 somestatus stop reason just information to hide 2, 3 Enrolling by Invitation Treatment Alopecia Areata (AA) 1 somestatus stop reason just information to hide 1 Completed Basic Science Healthy Volunteers (HV) 4 somestatus stop reason just information to hide
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
- Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Drug created at June 26, 2024 18:45 / Updated at June 27, 2024 01:29