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Displaying results 8661 - 8670 of 10000 in total
  1. Drug

    D-Glutamic Acid

    go.drugbank.com/drugs/DB02517
    Experimental

    Glutamic acid is the most common excitatory neurotransmitter in the central nervous system.

  2. Drug

    N-(carboxycarbonyl)-D-phenylalanine

    go.drugbank.com/drugs/DB08263
    Experimental

    N-(carboxycarbonyl)-D-phenylalanine is a solid. This compound belongs to the n-acyl-alpha amino acids. … These are compounds containing an alpha amino acid which bears an acyl group at its terminal nitrogen atom. It targets the protein hypoxia-inducible factor 1-alpha inhibitor.

    Synonyms: N-(carboxycarbonyl)-D-phenylalanine
  3. Drug

    Pamufetinib

    go.drugbank.com/drugs/DB20752
    Investigational

    The usage of the INN stem '-tinib' in the name indicates that Pamufetinib is a tyrosine kinase inhibitor. Pamufetinib is under investigation in clinical trial NCT04999761 (AB122 Platform Study).

  4. Drug

    Cixutumumab

    go.drugbank.com/drugs/DB12250
    Investigational

    IGF-IR is overexpressed in a variety of tumour types. … Cixutumumab has been used in trials studying the treatment of Lung Cancer, Malignant Neoplasm, Leukemia, Mast-Cell, Non-Small-Cell Lung Carcinoma, and Adenocarcinoma of the Prostate.

  5. Drug

    Halofuginone

    go.drugbank.com/drugs/DB04866
    InvestigationalVet approved

    Food and Drug Administration in March, 2000. … Halofuginone also effectively suppresses tumor progression and metastasis in mice.

  6. Drug

    (1H-indol-3-yl)-(2-mercapto-ethoxyimino)-acetic acid

    go.drugbank.com/drugs/DB03455
    Experimental

    These are compounds containing an acetic acid (or a derivative) linked to the C3 carbon atom of an indole. (1H-indol-3-yl)-(2-mercapto-ethoxyimino)-acetic acid is known to target interleukin-2.

  7. Drug

    Gemogenovatucel-T

    go.drugbank.com/drugs/DB17412
    Investigational

    Furin is a convertase involved in the activation of TGFβ-1 and TGFβ-2.[A255163] Gemogenovatucel-T is being investigated in the treatment of various cancers.

  8. Drug

    Tetrahydrofolic acid

    go.drugbank.com/drugs/DB00116
    InvestigationalNutraceutical

    It is a soluble coenzyme in many reactions, especially in the metabolism of amino acids and nucleic acids.

  9. Drug

    Vabametkib

    go.drugbank.com/drugs/DB21629
    Investigational

    Vabametkib is under investigation in clinical trial NCT05541822 (To Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetic Profile of ABN401 in Patients With Advanced Solid Tumors Harboring c-MET

  10. Drug

    Sapanisertib

    go.drugbank.com/drugs/DB11836
    Investigational

    Sapanisertib has been used in trials studying the treatment of HCC, Solid Tumor, Gliosarcoma, Liver Cancer, and Glioblastoma, among others.