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Displaying results 8681 - 8690 of 10000 in total
  1. Drug

    Androstenediol

    go.drugbank.com/drugs/DB01524
    ExperimentalIllicit

    Androstenediol is an intermediate in [testosterone] biosynthesis, found in the testis or the adrenal glands. … Androstenediol, derived from dehydroepiandrosterone by the reduction of the 17-keto group (17-hydroxysteroid dehydrogenases), is converted to testosterone by the oxidation of the 3-beta hydroxyl group

  2. Drug

    TM5614

    go.drugbank.com/drugs/DB16516
    Investigational

    PAI-1 is a marker of obesity, type 2 diabetes, and metabolic syndrome[L31673,A228793,A228798], and current studies are exploring downstream effects of its inhibition. … TM5614 inhibition of PAI-1, specifically, downregulates PCSK9 at the transcriptional level[A228793].

  3. Drug

    CEP-9722

    go.drugbank.com/drugs/DB14882
    Investigational

    CEP-9722 is under investigation in clinical trial NCT01345357 (Study of CEP-9722 in Combination With Gemcitabine and Cisplatin in Patients With Advanced Solid Tumors or Mantle Cell Lymphoma).

  4. Drug

    Renvistobart

    go.drugbank.com/drugs/DB19065
    Investigational

    Renvistobart is under investigation in clinical trial NCT02913313 (A Study of BMS-986207 Given Alone and in Combination With Nivolumab or With Nivolumab and Ipilimumab in Advanced Solid Tumors).

  5. Drug

    Dazostinag

    go.drugbank.com/drugs/DB18889
    Investigational

    Dazostinag is under investigation in clinical trial NCT04420884 (A Study of Dazostinag as Single Agent and Dazostinag in Combination With Pembrolizumab in Adults With Advanced or Metastatic Solid Tumors

    Synonyms: 7-Deazainosine, [P(R)]-2′-deoxy-2′-fluoro-5′-O-[(R)-hydroxymercaptophosphinyl]-P-thioadenylyl-(3′→5′)-7-fluoro-, cyclic (2′→5′)-nucleotide
  6. Drug

    Crisdesalazine

    go.drugbank.com/drugs/DB18405
    Experimental

    Categories: Anti-Inflammatory Agents, Non-Steroidal
  7. Drug

    Aniline

    go.drugbank.com/drugs/DB06728
    Investigational

    Aniline, phenylamine or aminobenzene is an organic compound with the formula C6H5NH2. Consisting of an amine attached to a benzene ring, aniline is the prototypical aromatic amine. … Being a precursor to many industrial chemicals, its main use is in the manufacture of precursors to polyurethane. Like most volatile amines, it possesses the somewhat unpleasant odour of rotten fish.

  8. Drug

    Cetrelimab

    go.drugbank.com/drugs/DB15421
    Investigational

    )-1 Monoclonal Antibody, as Monotherapy or in Combination With Erdafitinib in Japanese Participants With Advanced Solid Cancers). … Cetrelimab is under investigation in clinical trial NCT03547037 (A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of JNJ-63723283, an Anti-Programmed Cell Death (PD

  9. Drug

    Human growth hormone-releasing peptide 3

    go.drugbank.com/drugs/DB19227
    Investigational

    Human growth hormone-releasing peptide 3 is under investigation in clinical trial NCT00846872 (Effect of Continuous GHRP-3 Infusion at on GH-IGF-I System, Blood Pressure, Glucose, and Insulin Resistance

    Synonyms: L-argininamide, 2-methylalanyl-d-tryptophyl-d-prolyl-d-isoleucyl-
  10. Drug

    Bardoxolone

    go.drugbank.com/drugs/DB12651
    Investigational

    Bardoxolone has been used in trials studying the treatment of LYMPHOMA and Solid Tumors. … It is a synthetic triterpenoid and a highly potent activator of redox-sensitive signaling pathways that induce programmed cell death (apoptosis) in cancer cells that are under high levels of intrinsic