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Meloxicam
go.drugbank.com/drugs/DB00814ApprovedInvestigationalVet approvedIt is a preferential COX-2 inhibitor, purportedly reducing the risk of adverse gastrointestinal tract effects, however, this is a topic of controversy.[A190198,A190201] … [A190189] With a longer half-life than most other NSAIDS, it is a favorable option for those who require once-daily dosing. Meloxicam is available in oral, transdermal, and intravenous formulations.
Mixtures: MELOCAM DUO 7.5/20 MG TABLETAS RECUBIERTAS, MELOCAM DUO 15/20 TABLETASCategories: COX-2 Inhibitors, Selective Cyclooxygenase 2 Inhibitors (NSAIDs)Atezolizumab
go.drugbank.com/drugs/DB11595ApprovedInvestigational[L7489] Atezolizumab was granted FDA approval on 18 October 2016. … Atezolizumab is a humanized monoclonal antibody used to prevent the interaction of PD-L1 and PD-1, removing inhibition of immune responses seen in some cancers.
Products: TECENTRIQ CONCENTRATE FOR SOLUTION FOR INFUSION 1200 MG/ 20 ML, TECENTRIQ 1200 MG / 20 ML İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADETLetermovir
go.drugbank.com/drugs/DB12070ApprovedInvestigationalIt is currently marketed under the brand name Prevymis.[L1021] … Letermovir recieved approval from the FDA on November 8th, 2017 for use in prophylaxis of cytomegalovirus (CMV) infection in allogeneic hematopoietic stem cell transplant patients.
Categories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 SubstratesProducts: PREVYMİS 240 MG FİLM KAPLI TABLET, 28 ADET, PREVYMIS 240 MG SOLUCIÓN INYECTABLERuxolitinib
go.drugbank.com/drugs/DB08877ApprovedInvestigational[A229708] In 2014, it was approved for the treatment of polycythemia vera in adults who have an inadequate response to or are intolerant of [hydroxyurea] and in 2019, ruxolitinib was approved for use in … It is a potent and selective inhibitor of JAK1 and JAK2,[A229698] which are tyrosine kinases involved in cytokine signalling and hematopoiesis.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesProducts: JAKAVİ 10 MG TABLET, 56 ADET, JAKAVİ 10 MG TABLET, 168 ADETAzelastine
go.drugbank.com/drugs/DB00972ApprovedInvestigational[L8240,L8270] It is a racemic mixture, though there is no noted difference in pharmacologic activity between enantiomers, and was first granted FDA approval in 1996. … Azelastine, a phthalazine derivative, is an antihistamine available as an intranasal spray for the treatment of allergic and vasomotor rhinitis and as an ophthalmic solution for the treatment of allergic
Synonyms: 4-(p-Chlorobenzyl)-2-(hexahydro-1-methyl-1H-azepin-4-yl)-1-(2H)-phthalazinoneMixtures: DYMİSTA 137 MCG + 50 MCG BURUN SPREYİ, SÜSPANSİYON, 23 G, N-S-4Rasagiline
go.drugbank.com/drugs/DB01367ApprovedInvestigationalRasagiline is an irreversible inhibitor of monoamine oxidase and is used as a monotherapy in early Parkinson's disease or as an adjunct therapy in more advanced cases.
Synonyms: (R)-N-2-Propynyl-1-indanamine, (R)-indan-1-yl-prop-2-ynyl-amineCategories: Compounds used in a research, industrial, or household setting, Cytochrome P-450 SubstratesXylometazoline
go.drugbank.com/drugs/DB06694ApprovedIn some countries, it is available as combination products with [ipratropium], [domiphen], or [dexpanthenol]. … Xylometazoline is an imidazoline derivative [A228523] with sympathomimetic and nasal decongestant activity.
Mixtures: XYLAZOL PEDİYATRİK 0,5 MG/ML + 50 MG/ML BURUN SPREYİ, ÇÖZELTİ, 10 ML, nasic - Nasenspray 10 mg/500 mgCategories: Adrenergic alpha-2 Receptor AgonistsTenofovir disoproxil
go.drugbank.com/drugs/DB00300ApprovedInvestigationalThis drug is prescribed in combination with other drugs for the management of HIV infection as well as for Hepatitis B therapy. Tenofovir disoproxil was initially approved in 2001 [FDA label].
Mixtures: STRIBILD FILM COATED TABLET 150 MG/150 MG/200 MG/245 MG, TRUVADA 200 MG/245 MG FILM TABLET, 30 ADETCategories: Antivirals used in combination for the treatment of HIV infectionsSibutramine
go.drugbank.com/drugs/DB01105ApprovedIllicitWithdrawnIt is a centrally acting stimulant chemically related to amphetamines thus it is classified as a Schedule IV controlled substance in the United States. … Sibutramine (trade name Meridia in the USA, Reductil in Europe and other countries), usually as sibutramide hydrochloride monohydrate, is an orally administered agent for the treatment of obesity.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: SEROTRAMIN CAPSULAS 20 MG., SINHABIT 10 MGClotrimazole
go.drugbank.com/drugs/DB00257ApprovedInvestigationalVet approvedIt is available in various preparations, including creams, pessaries, and troche formulations (slowly dissolving tablets). … Clotrimazole's antimycotic properties were discovered in the late 1960s [A174094].
Synonyms: 1-(α-(2-Chlorophenyl)benzhydryl)imidazole, 1-((2-Chlorophenyl)diphenylmethyl)-1H-imidazoleMixtures: Imazol duo 10 mg/g + 2,5 mg/g Creme, LINDAZOL-2 ®