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Cerliponase alfa
go.drugbank.com/drugs/DB13173ApprovedInvestigational[L51339] It was also approved by the EMA on May 30, 2017 [L51324] and by Health Canada on December 19, 2018. … [A264354, A264369] As a recombinant human TPP1, cerliponase alfa is used as an enzyme replacement therapy to restore the levels of TPP1 in patients with CLN2.[L51339]
Categories: Hydrolytic Lysosomal N-terminal Tripeptidyl PeptidaseViloxazine
go.drugbank.com/drugs/DB09185ApprovedInvestigationalWithdrawn[L41685] For decades, an immediate-release formulation of viloxazine has been used in Europe as an antidepressant. … In the US, viloxazine was assigned an orphan drug designation in 1984 under the brand name CATATROL: while this product was intended to treat cataplexy and narcolepsy, the drug was never approved for these
Glycine
go.drugbank.com/drugs/DB00145ApprovedInvestigationalNutraceuticalVet approvedIt is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. It is also a fast inhibitory neurotransmitter.
Mixtures: POLİNUTHREE EN-550 ELEKTROLİTLİ AMİNOASİT ÇÖZELTİSİ, GLUKOZ ÇÖZELTİSİ, VE LİPİD EMÜLSİYONU, 1000 ML, POLİNUTHREE EN-550 ELEKTROLİTLİ AMİNOASİT ÇÖZELTİSİ, GLUKOZ ÇÖZELTİSİ, VE LİPİD EMÜLSİYONU, 1500 MLAvacopan
go.drugbank.com/drugs/DB15011ApprovedInvestigational[A240249, A240254] Despite complex pathophysiology, studies over the past ~2 decades have identified a key role for the alternative complement pathway and, in particular, the interaction between the anaphylatoxin … [L38919] On January 19, 2022, the European Commission approved avacopan for the treatment of adult patients with severe, active granulomatosis polyangiitis (GPA) or microscopic polyangiitis (MPA) - the
Dextran
go.drugbank.com/drugs/DB09255ApprovedInvestigationalVet approvedDextran 75 is a complex branched glucan with an average molecular weight 75000 Daltons. … When labelled with technetium Tc99m, dextran 75 is intravenously administered as an imaging agent to detect and diagnose conditions in the vascular compartment such as pericardial effusion or ventricular
Mixtures: RHEOMACRODEX EN SOLUCIÓN GLUCOSADA, RHEOMACRODEX EN SOLUCIÓN SALINA ISOTÓNICACategories: Compounds used in a research, industrial, or household settingManganese cation
go.drugbank.com/drugs/DB06757ApprovedInvestigationalNutraceutical[L50667] Apart from its use in human health, has been used in the mining industry, welding, smelting, and the manufacture of batteries.[A263657] … [A263657] Manganese can be found in over-the-counter nutritional supplements and vitamins.[A263667] It is commonly used in total parenteral nutrition (TPN) therapy.
Mixtures: Coen.q10w.vit.c and E Beta-car.se Cu Zn Mn, Ribotin-EProducts: Micro MnAbiraterone
go.drugbank.com/drugs/DB05812ApprovedInvestigationalAbiraterone is a potent, irreversible, and selective inhibitor of 17 αhydroxylase/C17,20-lyase (CYP17), an enzyme expressed in testicular, adrenal, and prostatic tumour tissues, to regulate androgen biosynthesis … [A3811, A260880, L40968] Abiraterone was first approved by the FDA and EMA on April,[A260880] July,[L47745] and September 2011,[A260880] respectively.
Sodium oxybate
go.drugbank.com/drugs/DB09072ApprovedInvestigationalin May 2023. … [L46302] In some countries, sodium oxybate has been investigated and used in alcohol withdrawal syndrome (AWS) to aid abstinence maintenance in alcohol use disorders.[A251440, A251445]
Hexaminolevulinate
go.drugbank.com/drugs/DB06261ApprovedInvestigationalIn Europe, Hexaminolevulinate is marketed under the brand Hexvix®. … On May 28, 2010, the U.S.
Ambrisentan
go.drugbank.com/drugs/DB06403ApprovedInvestigationalIt is approved in Europe, Canada and the United States for use as a single agent to improve exercise ability and delay clinical worsening. … In addition, it is approved in the United States for use in combination with tadalafil to reduce the risks of disease progression, hospitalization and to improve exercise ability.