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PF-04691502
go.drugbank.com/drugs/DB11974InvestigationalPF-04691502 has been used in trials studying the treatment of Cancer, Breast Neoplasms, Early Breast Cancer (Phase 2), and Advanced Breast Cancer (Phase 1b).
Categories: Heterocyclic Compounds, 1-Ring, Phosphatidylinositol 3-Kinases, antagonists & inhibitorsAnifrolumab
go.drugbank.com/drugs/DB11976ApprovedInvestigationalAnifrolumab, or MEDI-546, is a type 1 interferon receptor (IFNAR) inhibiting IgG1κ monoclonal antibody indicated in the treatment of adults with moderate to severe systemic lupus erythematosus. … [A237079,L34929] Three monoclonal antibodies (anifrolumab, [rontalizumab], and [sifalimumab]) that target the type 1 interferon pathway entered clinical trials as potential treatments for systemic lupus
Categories: Type I Interferon Receptor AntagonistProducts: Saphnelo 300 mg/2 mL İnfüzyonluk Çözelti Hazırlamak İçin Konsantre, 1 ADETGDC-0623
go.drugbank.com/drugs/DB11982InvestigationalGDC-0623 has been used in trials studying the treatment of Solid Cancers.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingBenznidazole
go.drugbank.com/drugs/DB11989ApprovedInvestigationalBenznidazole was granted accelerated approval for the treatment of Chagas disease in children 2-12 years of age by the FDA on August 29, 2017.
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: ABALEA ®100 MGOmarigliptin
go.drugbank.com/drugs/DB11992InvestigationalOmarigliptin has been used in trials studying the treatment of Type 2 Diabetes Mellitus and Chronic Renal Insufficiency.
Categories: Heterocyclic Compounds, 1-RingDiacerein
go.drugbank.com/drugs/DB11994ApprovedInvestigationalWithdrawnDiacerein is a prodrug which is metabolized to rhein. … Diacerein is under investigation for the treatment of Insulin Resistance, Diabetes Mellitus (Type 2), and Diabetes-Related Complications.
Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 CYP2C9 InhibitorsProducts: FLAMTOR®, ARTOSAN® CAPSULAVosaroxin
go.drugbank.com/drugs/DB11999InvestigationalVosaroxin is under investigation for the treatment of Leukemia, Myeloid, Acute.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingAZD-4818
go.drugbank.com/drugs/DB12002InvestigationalAZD4818 has been used in trials studying the treatment of Chronic Obstructive Pulmonary Disease (COPD).
Categories: Heterocyclic Compounds, 1-RingFevipiprant
go.drugbank.com/drugs/DB12011InvestigationalFevipiprant has been used in trials studying the treatment of Asthma, Atopic Dermatitis, and Allergic Rhinitis.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingDinaciclib
go.drugbank.com/drugs/DB12021InvestigationalDinaciclib has been used in trials studying the treatment of rrMM, rrCLL, rrDLBCL, Solid Tumors, and Solid Neoplasm, among others.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring