GDC-0623

DB11982InvestigationalSmall molecule

GDC-0623 has been used in trials studying the treatment of Solid Cancers.

Mechanism: Pharmacologically active on Dual specificity mitogen-activated protein kinase kinase 1 and Dual specificity mitogen-activated protein kinase kinase 2
Curator reviewed
Formula / weight: C₁₆H₁₄FIN₄O₃ · 456.216 g/mol (avg)
Code names: GDC-0623

Resolves to

Compound

Structure

InChIKeyRFWVETIZUQEJEF-UHFFFAOYSA-NSMILESOCCONC(=O)C1=C(NC2=C(F)C=C(I)C=C2)N2C=NC=C2C=C1

Targets

What you can answer from here — as of July 07, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

1Clinical trialPhase, status and sponsor resolved per trial

14+ReferencesStructured and connected to the statements they support

Which drugs share a target with GDC-0623, and which of those have an active Phase 3 trial?

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