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Pegsunercept
go.drugbank.com/drugs/DB06611InvestigationalPegsunercept is used for treating rheumatoid arthritis. Phase II clinical trials were completed in January 2010.
Categories: Compounds used in a research, industrial, or household settingMepolizumab
go.drugbank.com/drugs/DB06612ApprovedInvestigationalEosinophils are involved in inflammatory immune responses, and prolonged hypereosinophilia (typically defined as absolute eosinophil levels of 1500/mm<sup>3</sup> or more) is associated with a spectrum … The pathogenesis of eosinophilia is complex, but IL-5 is recognized as a key cytokine involved in the differentiation, recruitment, activation, and prolonged survival of eosinophils in peripheral tissue
Categories: Interleukin-5 AntagonistProducts: NUCALA® 100MG/ML SOLUCION INYECTABLE, Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Enjektör (1 adet)Bosutinib
go.drugbank.com/drugs/DB06616ApprovedInvestigationalBosutinib is a 7-alkoxy-3-quinolinecarbonitrile that functions as a potent, dual SRC and ABL tyrosine kinase inhibitor indicated for chronic myelogenous leukemia (CML), specifically Philadelphia chromosome-positive … Philadelphia chromosome is a hallmark of CML due to the reciprocal translocation t(9;22)(q34;q11), resulting in a BCR-ABL fusion protein.
Synonyms: 4-((2,4-dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(4-methyl-1-piperazinyl)propoxy)-3-quinolinecarbonitrileCategories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexFlupirtine
go.drugbank.com/drugs/DB06623InvestigationalFlupirtine is a pyridine derivative that is in clinical use as a nonopioid analgesic. It was approved for the treatment of pain in 1984 in Europe.
Categories: Heterocyclic Compounds, 1-RingIMA901
go.drugbank.com/drugs/DB06628InvestigationalIMA901 is a vaccine consists of tumor-associated peptides (TUMAPs).
Isavuconazonium
go.drugbank.com/drugs/DB06636ApprovedInvestigationalIsavuconazonium is a second-generation triazole antifungal approved on March 6, 2015 by the FDA and July 2015 by the EMA for the treatment of adults with invasive aspergillosis and invasive mucormycosis … Isovuconazonium has excellent oral bioavailability, predictable pharmacokinetics, and a good safety profile, making it a reasonable alternative to its few other competitors on the market.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 CYP2B6 InducersProducts: CRESEMBA ® CAPSULAS, CRESEMBA® 200 MG POLVO LIOFILIZADO ESTERIL PARA RECONSTITUIRQuarfloxin
go.drugbank.com/drugs/DB06638InvestigationalCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingBevasiranib
go.drugbank.com/drugs/DB06642InvestigationalBevasiranib is a small interfering RNA (siRNA) targeting vascular endothelial growth factor A (VEGF-A).
Categories: Compounds used in a research, industrial, or household setting