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Iclepertin
go.drugbank.com/drugs/DB19058InvestigationalIclepertin is under investigation in clinical trial NCT05211947 (A Study to Test Long-term Safety of Iclepertin in People With Schizophrenia Who Took Part in a Previous CONNEX Study).
Esaxerenone
go.drugbank.com/drugs/DB15207InvestigationalEsaxerenone is under investigation in clinical trial NCT02722265 (Long-term Study of CS-3150 as Monotherapy or in Combination With Other Antihypertensive Drug in Japanese Patients With Essential Hypertension
Balcinrenone
go.drugbank.com/drugs/DB15418InvestigationalAZD-9977 is under investigation in clinical trial NCT03843060 (A Phase 1 Study to Assess the Pharmacokinetics of AZD9977 Administered Alone and in Combination With Itraconazole in Healthy Volunteers).
Gemogenovatucel-T
go.drugbank.com/drugs/DB17412InvestigationalFurin is a convertase involved in the activation of TGFβ-1 and TGFβ-2.[A255163] Gemogenovatucel-T is being investigated in the treatment of various cancers. … Gemogenovatucel-T is a bi-shRNA furin/Granulocyte Macrophage Colony Stimulating Factor (GMCSF) Augmented autologous tumour cell vaccine.
AMY-101
go.drugbank.com/drugs/DB14803InvestigationalAMY-101 is under investigation in clinical trial NCT03694444 (A Study of the C3 Complement Inhibitor AMY-101 in Adults With Gingivitis). … AMY-101, also known as compstatin 40, is a peptidic inhibitor of the central complement component C3.
Timdarpacept
go.drugbank.com/drugs/DB17544Investigational[A257261] IMM01 is under investigation in clinical trial NCT05140811 (A Study of IMM01 Combined With Azacitidine in Patients With Acute Myeloid Leukemia and Myelodysplastic Syndrome). … IMM01 is a recombinant human signal regulatory protein α (SIRPα) IgG 1 fusion protein.
Navamepent
go.drugbank.com/drugs/DB21096InvestigationalNavamepent is a small molecule drug. … Navamepent is under investigation in clinical trial NCT02329743 (Efficacy and Safety of RX-10045 Ophthalmic Solution for Ocular Inflammation and Pain in Cataract Surgery).
Aderbasib
go.drugbank.com/drugs/DB21288InvestigationalAderbasib is a small molecule drug. … Aderbasib is under investigation in clinical trial NCT01254136 (Safety and Efficacy of INCB007839 With Trastuzumab and Vinorelbine in Patients With Metastatic HER2+ Breast Cancer).