Aderbasib

DB21288InvestigationalSmall molecule

Aderbasib is a small molecule drug. Aderbasib is under investigation in clinical trial NCT01254136 (Safety and Efficacy of INCB007839 With Trastuzumab and Vinorelbine in Patients With Metastatic HER2+ Breast Cancer).... Aderbasib has a monoisotopic molecular weight of 416.21 Da.

Formula / weight: C₂₁H₂₈N₄O₅ · 416.478 g/mol (avg)
Code names: INCB-007839

Resolves to

Compound

UNIIV9YL6NEJ3GCAS791828-58-5ChEMBLCHEMBL2103790ChEBI750464PubChem16070111

Structure

InChIKeyDJXMSZSZEIKLQZ-IRXDYDNUSA-NSMILESCOC(=O)N1CC2(CC2)C[C@@H]([C@H]1C(=O)N1CCN(CC1)C1=CC=CC=C1)C(=O)NO

Targets

O14672ADAM10P78536ADAM17

What you can answer from here — as of September 23, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

2Clinical trialsPhase, status and sponsor resolved per trial

2+ReferencesStructured and connected to the statements they support

Which drugs share a target with Aderbasib, and which of those have an active Phase 3 trial?

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