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Displaying results 871 - 880 of 3888 in total
  1. Drug

    Gadopentetic acid

    go.drugbank.com/drugs/DB00789
    ApprovedInvestigational

    A complex of gadolinium with a chelating agent, diethylenetriamine penta-acetic acid (DTPA see pentetic acid), that is given to enhance the image in cranial and spinal MRIs.

  2. Indication

    Tuberous Sclerosis Complex with Renal angiomyolipoma

    go.drugbank.com/conditions/DBCOND0025534
    Drugs: Everolimus
    Synonyms: Tuberous Sclerosis Complex with Renal angiomyolipoma
  3. Drug

    Pegunigalsidase alfa

    go.drugbank.com/drugs/DB14992
    ApprovedInvestigational

    [A259347,A259352] In May 2023, the EMA granted marketing authorization to pegunigalsidase alfa in the European Union (EU) for the treatment of adult patients with Fabry disease. … Furthermore, the pegylation of pegunigalsidase alfa promotes higher stability and a longer half-life, allowing it to reach target organs with a lower dose and frequency of administration.

  4. Target

    Copper-containing nitrite reductase

    go.drugbank.com/bio_entities/BE0001495
    TargetAchromobacter cycloclastes

    Polypeptides: Copper-containing nitrite reductaseFunction: copper ion binding
  5. Target

    Copper-containing nitrite reductase

    go.drugbank.com/bio_entities/BE0002802
    TargetAlcaligenes xylosoxydans xylosoxydans

    Polypeptides: Copper-containing nitrite reductaseSynonyms: Dissimilatory copper-containing nitrite reductase
  6. Target

    Copper-transporting ATPase 2

    go.drugbank.com/bio_entities/BE0003664
    TransporterHumans

    Copper ion transmembrane transporter involved in the export of copper out of the cells. … It is involved in copper homeostasis in the liver, where it ensures the efflux of copper from hepatocytes into the bile in response to copper overload

    Polypeptides: Copper-transporting ATPase 2Synonyms: Copper pump 2
  7. Target

    CMV DNA Terminase Complex

    go.drugbank.com/bio_entities/BE0010221
    TargetHuman Cytomegalovirus

    Forms a tripartite terminase complex together with TRM2 and TRM3 in the host cytoplasm. Once the complex reaches the host nucleus, it interacts with the capsid portal vertex. … Forms a tripartite terminase complex together with TRM1 and TRM3 in the host cytoplasm. Once the complex reaches the host nucleus, it interacts with the capsid portal vertex.

  8. Drug

    Birch bark extract

    go.drugbank.com/drugs/DB16536
    ApprovedInvestigational

    [A249945] Birch bark extract is obtained from the white part of the birch tree bark, and the main species of trees used for production are _Betula pendula_ Roth (silver birch) and _Betula pubescens_ Ehrh … [L50031] The EMA marketing authorization for Episalvan[L42370] was withdrawn by the manufacturer in 2022.

    Categories: Complex Mixtures
  9. Drug

    Lorlatinib

    go.drugbank.com/drugs/DB12130
    ApprovedInvestigational

    It was subsequently approved by the EMA in 2019 for the treatment of select patients with previously treated advanced ALK-positive non-small cell lung cancer, followed by an expanded approval in 2022 to

  10. Drug

    Prasterone

    go.drugbank.com/drugs/DB01708
    ApprovedInvestigationalNutraceutical

    Prasterone, also known as dehydroepiandrosterone (DHEA) is a major C19 steroid produced by the adrenal cortex. It is also produced in small quantities in the testis and the ovary. Dehydroepiandrosterone (DHEA) can be converted to testost...

    Categories: Genito Urinary System and Sex Hormones, Sex Hormones and Modulators of the Genital System