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Displaying results 871 - 880 of 10000 in total
  1. Drug

    Disperse Blue 106

    go.drugbank.com/drugs/DB14203
    Approved

    Disperse Blue 106 is used in allergenic testing.

    Synonyms: 5-Nitro-2-(2-methyl-4-(N-ethyl-N-(2-hydroxyethyl)amino)phenylazo)thiazole
  2. Drug

    Chlorthalidone

    go.drugbank.com/drugs/DB00310
    ApprovedInvestigational

    [A173863] In particular, the ALLHAT trial confirmed the role of thiazide diuretics as first-line therapy and demonstrated that chlorthalidone had a statistically significant lower incidence of stroke and … [A176324] Chlorthalidone is considered first-line therapy for management of uncomplicated hypertension as there is strong evidence from meta-analyses that thiazide diuretics such as chlorthalidone reduce

    Mixtures: ATENOLOLO CLORTALIDONE EG, ATENOLOLO CLORTALIDONE EGCategories: Heterocyclic Compounds, 2-Ring
  3. Drug

    Furazolidone

    go.drugbank.com/drugs/DB00614
    InvestigationalVet approved

    (From Martindale, The Extra Pharmacopoeia, 30th ed, p514) … A nitrofuran derivative with antiprotozoal and antibacterial activity. Furazolidone binds bacterial DNA which leads to the gradual inhibition of monoamine oxidase.

    Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, Heterocyclic Compounds, 1-RingSynonyms: N-(5-Nitro-2-furfurylidene)-3-amino-2-oxazolidone, 5-Nitro-N-(2-oxo-3-oxazolidinyl)-2-furanmethanimine
  4. Drug

    Exaluren

    go.drugbank.com/drugs/DB17631
    Investigational

    Synonyms: 6-(R)-Methyl-5-O-(5-amino-5,6-dideoxy-a-L-talofuranosyl)-paromamine, 6'-(R)-Methyl-5-O-(5-amino-5,6-dideoxy-a-L-talofuranosyl)-paromamineCategories: Heterocyclic Compounds, 1-Ring
  5. Drug

    Bioymifi

    go.drugbank.com/drugs/DB17493
    Experimental

    Upon binding to the death receptor 5 (DR5) on cancer cells, bioymifi triggers apoptosis, possibly through a caspase-dependent pathway. Bioymifi is currently being investigated as an anti-tumor agent. … Bioymifi is a small molecule that acts as a tumor necrosis factor-related apoptosis-induced ligand (TRAIL) mimetic.

    Categories: Heterocyclic Compounds, 2-RingSynonyms: 5-(5-((3-(4-bromophenyl)-2-imino-4-oxothiazolidin-5-ylidene)methyl)furan-2-yl)isoindoline-1,3-dione, 5-[5-[(Z)-[3-(4-bromophenyl)-2-imino-4-oxo-1,3-thiazolidin-5-ylidene]methyl]furan-2-yl]isoindole-1,3-dione
  6. Drug

    Depemokimab

    go.drugbank.com/drugs/DB18846
    ApprovedInvestigational

    [A275338] Depemokimab blocks interleukin-5 (IL-5), a key cytokine that regulates eosinophil maturation, survival, and recruitment. … Depemokimab is a humanized Immunoglobulin G1 (IgG1) monoclonal antibody and a long-acting drug.

    Categories: Interleukin-5 AntagonistSynonyms: Immunoglobulin g1, anti-(human interleukin 5) (human-mus musculus monoclonal gsk3511294 .gamma.1-chain), disulfide with human-mus musculus monoclonal gsk3511294 .kappa.-chain, dimer
  7. Drug

    STX-107

    go.drugbank.com/drugs/DB16943
    Investigational

    Synonyms: 3-Fluoro-5-(5-((2-methylthiazol-4-yl)ethynyl)pyridin-2-yl)benzonitrile, 3-fluoro-5-[5-[2-(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridin-2-yl]benzonitrile
  8. Drug

    Varoglutamstat

    go.drugbank.com/drugs/DB18785
    Investigational

    Synonyms: (5s)-1-(1h-benzimidazol-5-yl)-5-(4- propoxyphenyl)imidazolidin-2-one, (s)-1-(1h-benzimidazol-5-yl)-5-(4-propoxyphenyl)imidazolidin-2-one
  9. Drug

    AB-8939

    go.drugbank.com/drugs/DB17115
    Investigational

    Synonyms: 1-(4-(2-(5-ethoxymethyl-2-methyl-phenylamino)-oxazol-5-yl)-phenyl)-imidazolidin-2-one, 2-imidazolidinone, 1-(4-(2-((5-(ethoxymethyl)-2-methylphenyl)amino)-5-oxazolyl)phenyl)-
  10. Drug

    Streptomycin

    go.drugbank.com/drugs/DB01082
    ApprovedInvestigationalVet approved

    Streptomycin, an antibiotic derived from _Streptomyces griseus_, was the first aminoglycoside to be discovered and used in practice in the 1940s. … [A233325,A233390] Selman Waksman and eventually Albert Schatz were recognized with the Nobel Prize in Medicine for their discovery of streptomycin and its antibacterial activity.

    Categories: Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexSynonyms: 2,4-diguanidino-3,5,6-trihydroxycyclohexyl 5-deoxy-2-O-(2-deoxy-2-methylamino-alpha-L-glucopyranosyl)-3-C-formyl-beta-L-lyxopentanofuranoside