STX-107

DB16943InvestigationalSmall molecule

STX-107: Overview.

Mechanism: Pharmacologically active on Metabotropic glutamate receptor 5
Curator reviewed
Formula / weight: C₁₈H₁₀FN₃S · 319.36 g/mol (avg)
Also known as: 3-Fluoro-5-(5-((2-methylthiazol-4-yl)ethynyl)pyridin-2-yl)benzonitrile · 3-fluoro-5-[5-[2-(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridin-2-yl]benzonitrile
Code names: STX-107

Resolves to

Compound

Structure

InChIKeySYOSUEIMOYEGKU-UHFFFAOYSA-NSMILESCC1=NC(=CS1)C#CC1=CC=C(N=C1)C1=CC(=CC(F)=C1)C#N

Targets

What you can answer from here — as of August 30, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

3Clinical trialsPhase, status and sponsor resolved per trial

2+ReferencesStructured and connected to the statements they support

Which drugs share a target with STX-107, and which of those have an active Phase 3 trial?

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