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Displaying results 8791 - 8800 of 10000 in total
  1. Drug

    Tisotumab vedotin

    go.drugbank.com/drugs/DB16732
    ApprovedInvestigational

    Tisotumab vedotin is a tissue factor-directed antibody-drug conjugate (ADC) comprised of an anti-tissue factor (TF) human IgG1-kappa antibody conjugated to monomethyl auristatin E (MMAE), a microtubule-disrupting … agent, via a protease-cleavable valine-citrulline linker.

    Categories: P-glycoprotein substrates, Cytochrome P-450 Substrates
  2. Drug

    Allogeneic processed thymus tissue

    go.drugbank.com/drugs/DB16736
    Approved

    [L38929] Congenital athymia is a rare condition that leads to the absence of a thymus at birth and a high premature mortality rate, with patients typically dying by age two or three. … As part of the immune system, the thymus is an organ responsible for the maturation and selection of T cells [A239814]; thus, patients without a functional thymus experience profound immunodeficiency and

  3. Drug

    MM3122

    go.drugbank.com/drugs/DB16737
    Experimental

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  4. Drug

    Prolgolimab

    go.drugbank.com/drugs/DB16740
    Investigational

    Categories: PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitors, PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitors
  5. Drug

    CP-96345

    go.drugbank.com/drugs/DB16744
    Experimental

    Categories: Substance P, antagonists & inhibitors
  6. Drug

    Plant-based virus-like particles, recombinant, adjuvanted COVID-19 vaccine

    go.drugbank.com/drugs/DB16757
    Approved

    [L40694] It is composed of VLPs expressing SARS-CoV-2 spike protein trimers (stabilized in a pre-fusion conformation) and is mixed with the AS03 adjuvant system prior to administration. … [A245819] Plant-based VLPs offer a number of advantages as compared to other vaccine platforms, including speed and ease of manufacturing and increased immunogenicity.

    Synonyms: Recombinant SARS-CoV-2 spike (S)-protein virus-like particle
  7. Drug

    STF-31

    go.drugbank.com/drugs/DB16761
    Experimental

    Categories: Heterocyclic Compounds, 1-Ring
  8. Drug

    Tyrphostin B44

    go.drugbank.com/drugs/DB16762
    Experimental

    Synonyms: Tyrphostin B-44Categories: Heterocyclic Compounds, 2-Ring
  9. Drug

    Morin

    go.drugbank.com/drugs/DB16770
    Experimental

    Synonyms: 2-(2,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4h-1-benzopyran-4-one, Natural yellow 8Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  10. Drug

    Rhamnetin

    go.drugbank.com/drugs/DB16772
    Experimental

    Synonyms: 7-O-Methylquercetin, 7-MethoxyquercetinCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring