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Displaying results 8801 - 8810 of 10000 in total
  1. Drug

    Ertiprotafib

    go.drugbank.com/drugs/DB06521
    Experimental

    Ertiprotafib belongs to a novel class of insulin sensitizers developed for treatment of type 2 diabetes. … In insulin-resistant rodent models, ertiprotafib and a close analog lowered both fasting blood glucose and insulin levels and improved glycemic excursion during an oral glucose tolerance test.

    Categories: Heterocyclic Compounds, 1-Ring
  2. Drug

    Ocinaplon

    go.drugbank.com/drugs/DB06529
    Experimental

    Categories: Heterocyclic Compounds, 1-Ring
  3. Drug

    HNM01

    go.drugbank.com/drugs/DB06531
    Experimental

    The drug hNM01, a humanized monoclonal antibody developed by SRD Pharmaceuticals, Inc., targets the V(3) region of the HIV-1 envelope protein gp120, functioning as an HIV replication inhibitor. … It entered Phase 1 clinical trials for the treatment of HIV infections but was discontinued during this phase

  4. Drug

    ZD4407

    go.drugbank.com/drugs/DB06539
    Experimental

    The drug ZD4407, an antiasthmatic developed by AstraZeneca, functions as a 5-lipoxygenase inhibitor. … It entered Phase 1 clinical trials for chronic obstructive pulmonary disease (COPD) in the United Kingdom but was discontinued during this phase in March 2003

    Synonyms: 1,3-DIHYDRO-1-METHYL-5-((4-((2S,4R)-TETRAHYDRO-4-HYDROXY-2-METHYL-2H-PYRAN-4-YL)-2-THIENYL)THIO)-2H-INDOL-2-ONE, 5-(4-((2S,4R)-4-HYDROXY-2-METHYLOXAN-4-YL)THIOPHEN-2-YL)SULFANYL-1-METHYL-3H-INDOL-2-ONE
  5. Drug

    Atibuclimab

    go.drugbank.com/drugs/DB06546
    Investigational

    Atibuclimab (IC14) is a chimeric CD14 antibody investigated for the treatment of patients with severe sepsis.

    Synonyms: IMMUNOGLOBULIN G4, ANTI-(HUMAN CD14 ANTIGEN) (HUMAN-MUS MUSCULUS MONOCLONAL IC14 .GAMMA.4-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL IC14 .KAPPA.-CHAIN, DIMER
  6. Drug

    Minodronic acid

    go.drugbank.com/drugs/DB06548
    Investigational

    Categories: Heterocyclic Compounds, 1-Ring
  7. Drug

    Anpocogin

    go.drugbank.com/drugs/DB06552
    Investigational

    Recombinant nematode anticoagulant protein c2 (rNAPc2) is a specific inhibitor of tissue factor (TF)/factor VIIa complex with novel antithrombotic activity. [A175642]

    Synonyms: Recombinant nematode anticoagulant protein-2
  8. Drug

    Gaboxadol

    go.drugbank.com/drugs/DB06554
    Investigational

    Gaboxadol also known as 4,5,6,7-tetrahydroisoxazolo(5,4-c)pyridin-3-ol (THIP) is an experimental sleep aid drug developed by Lundbeck and Merck, who reported increased deep sleep without the reinforcing … It acts on the GABA system, but in a seemingly different way from benzodiazepines and other sedatives.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 4,5,6,7-tetrahydroisoxazolo(5,4-c)pyridin-3-ol
  9. Drug

    AM365

    go.drugbank.com/drugs/DB06564
    Experimental

    Detiviciclovir (AM365) is an antiviral nucleoside analogue.

    Synonyms: 2-((2-AMINO-9H-PURIN-9-YL)METHYL)PROPANE-1,3-DIOL
  10. Drug

    Rebimastat

    go.drugbank.com/drugs/DB06573
    Investigational

    Categories: Heterocyclic Compounds, 1-Ring