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Gemogenovatucel-T
go.drugbank.com/drugs/DB17412InvestigationalFurin is a convertase involved in the activation of TGFβ-1 and TGFβ-2.[A255163] Gemogenovatucel-T is being investigated in the treatment of various cancers.
Vabametkib
go.drugbank.com/drugs/DB21629InvestigationalVabametkib is under investigation in clinical trial NCT05541822 (To Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetic Profile of ABN401 in Patients With Advanced Solid Tumors Harboring c-MET
AZD3409
go.drugbank.com/drugs/DB04893ExperimentalAZD3409 is a farnesyl-transferase inhibitor (FAR) indicated for the treatment of solid tumors. Phase I trials were initiated January 2003, and were ongoing as of February 2004. As of February 2007 the development of AZD3409 had been disc...
Ortataxel
go.drugbank.com/drugs/DB11669InvestigationalOrtataxel has been used in trials studying the treatment of Lymphoma, Lung Cancer, Glioblastoma, and Kidney Cancer.
Menaquinone 6
go.drugbank.com/drugs/DB14936InvestigationalMenaquinone 6 is under investigation in clinical trial NCT01194778 (Comparison of Efficacy of Different Dosages Vitamin K2).
Pexmetinib
go.drugbank.com/drugs/DB16294InvestigationalPexmetinib is under investigation in clinical trial NCT04074967 (Study of ARRY-614 Plus Either Nivolumab or Ipilimumab).
Tetrafluoroborate
go.drugbank.com/drugs/DB16340InvestigationalTetrafluoroborate is under investigation in clinical trial NCT02907073 (Positron Emission Tomography (PET) Imaging Studies With NIS Reporter).
Tusamitamab ravtansine
go.drugbank.com/drugs/DB17448InvestigationalTusamitamab ravtansine is an antibody-drug conjugate that targets carcinoembryonic antigen-related cell adhesion molecule-5 (CEACAM5).
Crefmirlimab
go.drugbank.com/drugs/DB17577InvestigationalCrefmirlimab is an anti-human CD8 probe targeting the CD8 antigen, for the diagnosis of various cancers.
Synonyms: Iab22m2c (antibody fragment against the human cd8-antigen on cd8-positive t-cells)PYX-201
go.drugbank.com/drugs/DB18382InvestigationalPYX-201 is an antibody-drug conjugate directed against the extra domain-B splice variant of fibronectin.