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Gedivumab
go.drugbank.com/drugs/DB15277InvestigationalGedivumab is under investigation in clinical trial NCT01877785 (A Study of MHAA4549A to Assess Safety And Pharmacokinetics in Healthy Volunteers).
Exicorilant
go.drugbank.com/drugs/DB16162InvestigationalExicorilant is under investigation in clinical trial NCT03437941 (Study to Evaluate CORT125281 in Combination With Enzalutamide in Patients With Mcrpc).
TNP-2092
go.drugbank.com/drugs/DB16312InvestigationalTNP-2092 is under investigation in clinical trial NCT03964493 (TNP-2092 to Treat Acute Bacterial Skin and Skin Structure Infection).
PXT 3003
go.drugbank.com/drugs/DB16745InvestigationalPXT 3003 is in phase 3 clinical trials for the treatment of Charcot-Marie-Tooth disease type 1A in adults.
AMZ002
go.drugbank.com/drugs/DB17017InvestigationalAMZ002 is a sterile injectable hormone developed as a purified synthetic polypeptide alternative to current FDA-approved epileptic seizure treatments.
DSP107
go.drugbank.com/drugs/DB17501InvestigationalDSP107 is a bi-functional, trimeric, fusion protein composed of sequences from the extracellular domain of SIRPα and 4-1BBL.
SIS-101-ADO
go.drugbank.com/drugs/DB18085ExperimentalSIS-101-ADO is a siRNA therapeutic under investigation for the treatment of Autosomal Dominant Osteopetrosis Type 2 (ADO2).[L48091]
Xaluritamig
go.drugbank.com/drugs/DB18137InvestigationalXaluritamig is a novel humanized bispecific T cell recruiting antibody cross-reactive to human and nonhuman primate STEAP1 and CD3.
Synonyms: immunoglobulin G1-scFv-CH/G1-kappa, anti-[Homo sapiens STEAP1 (STEAP family member 1, six transmembrane epithelial antigen of the prostate 1, STEAP1 metalloreductase) and anti-[Homo sapiens CD3, bispecificTSHA-105
go.drugbank.com/drugs/DB18328InvestigationalTSHA-105 is an adeno-associated virus serotype 9 (AAV9) vector with an engineered transgene encoding the human SLC13A5 protein.
RC118
go.drugbank.com/drugs/DB18428InvestigationalRC118 is an antibody-drug conjugate that consists of a recombinant humanized IgG1 anti-Claudin18.2 monoclonal antibody conjugated to MMAE.
Synonyms: Recombinant humanized anti-MSLN monoclonal antibody- monomethyl auristatin E conjugate