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Displaying results 8871 - 8880 of 9686 in total
  1. Drug

    LMB-100

    go.drugbank.com/drugs/DB18591
    Investigational

    LMB-100 is a is an antibody-toxin conjugate with an antimesothelin Fab linked to a 24-kilodalton portion of Pseudomonas exotoxin A with mutations that decrease immunogenicity.

  2. Drug

    INH-A21

    go.drugbank.com/drugs/DB18598
    Experimental

    INH-A21 is a human staphylococcal immunoglobulin

  3. Drug

    ISTH0036

    go.drugbank.com/drugs/DB18606
    Investigational

    ISTH0036 is a synthetic 14-mer phosphorothioate antisense oligonucleotide directed against TGF-beta2 mRNA

  4. Drug

    P-42 peptide

    go.drugbank.com/drugs/DB18610
    Experimental

    P-42 peptide is a synthetic 23 amino acid peptide AASSGVSTPGSAGHDIITEQPRS derived from the Huntingtin protein

  5. Drug

    IDUA-RTB

    go.drugbank.com/drugs/DB18612
    Experimental

    RTB-IDUA is a fusion protein of alpha-L-iduronidase (IDUA) and ricin transport subunit B (RTB).

  6. Drug

    AOC 1001

    go.drugbank.com/drugs/DB18620
    Investigational

    Delpacibart (AOC 1001) is being investigated in a global study for the treatment of Myotonic Dystrophy type 1 (DM1) in clinical trial NCT06411288

  7. Drug

    AOC-1020

    go.drugbank.com/drugs/DB18621
    Investigational

    AOC-1020 is an antibody oligonucleotide conjugate, comprised of a human transferrin receptor 1 targeting, effector function null, humanized IgG1 antibody, a MCC maleimide linker, and a double-stranded

    Synonyms: An antibody oligonucleotide conjugate, comprised of a human transferrin receptor 1 targeting, effector function null, humanized IgG1 antibody, a MCC maleimide linker, and a double-stranded siRNA oligonucleotide
  8. Drug

    SLN500

    go.drugbank.com/drugs/DB18636
    Experimental

    SLN500 is a synthetic double-strand small interfering ribonucleic acid (siRNA) oligonucleotide drug directed against C3 messenger RNA

  9. Drug

    AVR-RD-04

    go.drugbank.com/drugs/DB18644
    Experimental

    It consists of autologous CD34+ enriched cells transduced with a lentiviral vector containing RNA resulting in codon-optimized cDNA encoding for functional human cystinosin.

    Synonyms: autologous CD34+ enriched cells transduced with a lentiviral vector containing RNA resulting in codon-optimized cDNA encoding for functional human cystinosin
  10. Drug

    Divesiran

    go.drugbank.com/drugs/DB18646
    Investigational

    Divesiran is a synthetic double-stranded siRNA oligonucleotide directed against TMPRSS6 mRNA and covalently linked to a ligand containing 3 N-acetylgalactosamine residues.