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Dovramilast
go.drugbank.com/drugs/DB16242InvestigationalDovramilast is under investigation in clinical trial NCT01300208 (To Evaluate the Preliminary Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Efficacy of CC-11050 in Subjects With Discoid
Synonyms: Cyclopropanecarboxamide, N-[2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-2,3-dihydro-3-oxo-1H-isoindol-4-yl]-, N-{2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2- (methanesulfonyl)ethyl]-3-oxo-2,3-dihydro-1H-isoindol- 4-yl}cyclopropanecarboxamideTU-100
go.drugbank.com/drugs/DB12467InvestigationalTU-100 has been used in trials studying the treatment of Abdominal Pain, Colonic Transit, Crohn's Disease, Rectal Sensation, and Gastric Emptying, among others.
Categories: DNA Topoisomerases, Type IIRisuteganib
go.drugbank.com/drugs/DB14911InvestigationalRisuteganib is under investigation in clinical trial NCT02348918 (Phase 2 Randomized Clinical Trial of LuminateĀ® as Compared to AvastinĀ® in the Treatment of Diabetic Macular Edema).
PCS-499
go.drugbank.com/drugs/DB15122InvestigationalPCS-499 is under investigation in clinical trial NCT01487109 (A Phase 2 Study to Evaluate the Safety and Efficacy of CTP-499 in Type 2 Diabetic Nephropathy Patients).
Ontamalimab
go.drugbank.com/drugs/DB15298InvestigationalOntamalimab is under investigation in clinical trial NCT03627091 (Efficacy and Safety Study of SHP647 as Maintenance Treatment in Participants With Moderate to Severe Crohn's Disease (CARMEN CD 307)).
Sepofarsen
go.drugbank.com/drugs/DB16327InvestigationalSepofarsen is under investigation in clinical trial NCT03913143 (A Study to Evaluate Efficacy, Safety, Tolerability and Exposure After a Repeat-dose of Sepofarsen (QR-110) in LCA10 (ILLUMINATE)).
Tafolecimab
go.drugbank.com/drugs/DB16336InvestigationalTafolecimab is under investigation in clinical trial NCT04031742 (A Study to Evaluate Safety and Efficacy of IBI306, a PCSK9 Monoclonal Antibody in Chinese Subjects With Homozygous Familial Hypercholesterolemia
Uracil C-13
go.drugbank.com/drugs/DB16345InvestigationalUracil C-13 is under investigation in clinical trial NCT01677338 (Phase 2 Study to Evaluate the Preliminary Performance of the C13-URA Breath Test Kit in Dyspeptic Subjects).
Zampilimab
go.drugbank.com/drugs/DB16381InvestigationalZampilimab is under investigation in clinical trial NCT04335578 (A Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Efficacy of UCB7858 in Adult Kidney Transplant Recipients With Chronic Allograft
Mitoguazone
go.drugbank.com/drugs/DB12967InvestigationalMitoguazone has been used in trials studying the treatment of Lymphoma, HIV Infections, and Lymphoma, Non-Hodgkin.