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WP-1122
go.drugbank.com/drugs/DB17192InvestigationalWP-1122 is a prodrug of 2-deoxy-D-glucose (2-DG). It was granted FDA orphan designation for the treatment of glioblastoma multiforme.[L47361]
Synonyms: 3,6-di-O-acetyl-2-deoxy-D-glucopyranose, an acetic acid diester of 2-deoxy-D-glucoseATX-F8-117
go.drugbank.com/drugs/DB17712ExperimentalATX-F8-117 is an investigational peptide derived from Factor VIII. Developed by Apitope, it is being investigated for the treatment of hemophilia A.[L46163]
Lometrexol
go.drugbank.com/drugs/DB12769InvestigationalLometrexol has been used in trials studying the treatment of Lung Cancer, Drug/Agent Toxicity by Tissue/Organ, and Unspecified Adult Solid Tumor, Protocol Specific.
Categories: Heterocyclic Compounds, 2-RingTilsotolimod
go.drugbank.com/drugs/DB16341InvestigationalTilsotolimod is under investigation in clinical trial NCT03865082 (Study of Tilsotolimod in Combination With Nivolumab and Ipilimumab for the Treatment of Solid Tumors (ILLUMINATE-206)).
CC-115
go.drugbank.com/drugs/DB12740InvestigationalCC-115 has been used in trials studying the treatment of Prostate Cancer, Neoplasm Metastasis, Ewing's Osteosarcoma, Glioblastoma Multiforme, and Chronic Lymphocytic Leukemia, among others.
Categories: Heterocyclic Compounds, 1-RingDihydroxyacetone phosphate
go.drugbank.com/drugs/DB04326InvestigationalDihydroxyacetone phosphate is an important intermediate in lipid biosynthesis and in glycolysis. Dihydroxyacetone phosphate has been investigated for the treatment of Lymphoma, Large-Cell, Diffuse.
Synonyms: 1-hydroxy-3-(phosphonooxy)-2-Propanone, 1-Hydroxy-3-(phosphonooxy)acetoneOPC-51803
go.drugbank.com/drugs/DB05838ExperimentalOPC-51803 is the first nonpeptide vasopressin (AVP) V(2)-receptor-selective agonist. … It is useful therapeutic drug in the treatment of hypothalamic diabetes insipidus, nocturnal enuresis, and some kinds of urinary incontinence.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingEperisone
go.drugbank.com/drugs/DB08992InvestigationalIt is not approved for use in the United States, but is available in other countries like India, South Korea, and Bangladesh. … suppression of the pain reflex.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: (2RS)-1-(4-ethylphenyl)-2-methyl-3-(1-piperidyl)propan-1-oneAdavosertib
go.drugbank.com/drugs/DB11740InvestigationalMK-1775 has been used in trials studying the treatment of LYMPHOMA, Neoplasms, Ovarian Cancer, Tongue Carcinoma, and Adult Glioblastoma, among others.
Categories: Heterocyclic Compounds, 1-RingVerinurad
go.drugbank.com/drugs/DB11873InvestigationalVerinurad has been used in trials studying the basic science and treatment of Gout, Gout and Hyperuricemia, and Gout and Asymptomatic Hyperuricemia.
Categories: Heterocyclic Compounds, 1-Ring