Lometrexol

DB12769InvestigationalSmall molecule

Lometrexol has been used in trials studying the treatment of Lung Cancer, Drug/Agent Toxicity by Tissue/Organ, and Unspecified Adult Solid Tumor, Protocol Specific.

Formula / weight: C₂₁H₂₅N₅O₆ · 443.4531 g/mol (avg)
Code names: LY-264618

Resolves to

Compound

UNII6P3AVY8A7QCAS106400-81-1ChEMBLCHEMBL34412PubChem148138

Structure

InChIKeyZUQBAQVRAURMCL-DOMZBBRYSA-NSMILESNC1=NC(=O)C2=C(NC[C@H](CCC3=CC=C(C=C3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)C2)N1

Targets

P0ABQ4folA

What you can answer from here — as of September 23, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

49Drug interactionsStructured to mechanism, not free text

2Clinical trialsPhase, status and sponsor resolved per trial

2+ReferencesStructured and connected to the statements they support

Which drugs share a target with Lometrexol, and which of those have an active Phase 3 trial?

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