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AVX-001
go.drugbank.com/drugs/DB19194InvestigationalAVX-001 is under investigation in clinical trial NCT05164393 (Phase I/iia Trial to Evaluate AVX001 Gel in Doses of 1% or 3% Compared With Vehicle Over Four Weeks of Field-directed Treatment Period in Adult
Synonyms: 1-((2e,6z,9z,12z,15z)-octadeca-3,6,9,12,15-pentaen-1-thio)-3,3,3-trifluoroacetone, 2-propanone, 1,1,1-trifluoro-3-((2e,6z,9z,12z,15z)-2,6,9,12,15-octadecapentaenylthio)-Nelistotug
go.drugbank.com/drugs/DB19334Investigationalinvestigation in clinical trial NCT06062420 (A Platform Study of Novel Immunotherapy Combinations as First-line Treatment in Participants With PD-L1 Positive Recurrent/metastatic Squamous Cell Carcinoma of the
Synonyms: Nelistotug (immunoglobulin G1-kappa, anti-[Homo sapiens CD96 (T cell activation increased late expression, TACTILE, T-cell surface protein tactile)], Homo sapiens monoclonal antibody), Gamma1 heavy chain Homo sapiens (1-452) [VH(Homo sapiens IGHV1-69*01 (95.9%) -(IGHD)-IGHJ1*01 (90.9%) L123>T (117), CDR-IMGT [8.8.15](26-33.51-58.97-111)) (1-122) -Homo sapiens IGHG1*01 (100%), G1m17,1Alpibectir
go.drugbank.com/drugs/DB21561InvestigationalAlpibectir is under investigation in clinical trial NCT06748937 (A Study of the Early Effects, Safety, and Acceptability of Oral Alpibectir in Combination With Ethionamide).
Ranosidenib
go.drugbank.com/drugs/DB21727InvestigationalRanosidenib is under investigation in clinical trial NCT06387069 (A Study to Evaluate HMPL-306 in Patients With IDH1- and IDH2-mutated Acute Myeloid Leukemia).
SW033291
go.drugbank.com/drugs/DB32765Experimental[A275473, A275474] It has been found to increase prostaglandin E2 (PGE2) and is being investigated in accelerating of hematopoietic recovery and treating type 2 diabetes mellitus.[A275473, A275474]
2'-fluoro-5-ethylarabinosyluracil
go.drugbank.com/drugs/DB13030Investigational2'-fluoro-5-ethylarabinosyluracil (FAU) has been used in trials studying the treatment of Small Intestine Lymphoma, Stage IV Mantle Cell Lymphoma, Waldenström Macroglobulinemia, Splenic Marginal Zone Lymphoma
CDX-1135
go.drugbank.com/drugs/DB17607InvestigationalCDX-1135, formerly TP-10, is a soluble, recombinant human Complement Receptor Type 1 (sCR1) developed by Avant Immunotherapeutics (now Celldex).
SIG-207
go.drugbank.com/drugs/DB18547ExperimentalSIG-207 is a Cultured human retinal pigment epithelial cells (ARPE-19) genetically modified with a non-viral vector to express Human alpha-galactosidase A (alpha-Gal A), encapsulated within two-layer modified
Inactivated SARS-Cov-2 Vaccine
go.drugbank.com/drugs/DB15862InvestigationalDeveloped by Sinopharm's Wuhan Institute of Biological Products co., this vaccine consists of the WIV04 strain of SARS-CoV-2. … [A220158] Currently, the vaccine is being tested in Phase 3 clinical trial in Abu Dhabi (ChiCTR2000034780).[A219758]
Oxabolone cipionate
go.drugbank.com/drugs/DB13185ExperimentalOxabolone cipionate is the C17β cypionate ester and a prodrug of [DB01500]. A synthetic anabolic-androgenic (AAS) steroid, it is a derivative of 19-nortestosterone (nandrolone).
Synonyms: Cipionato de oxabolona