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Displaying results 8981 - 8990 of 9698 in total
  1. Drug

    NDX-3315

    go.drugbank.com/drugs/DB18671
    Investigational

    It is a technetium-99m radiolabeled [heparin].

  2. Drug

    Ozekibart

    go.drugbank.com/drugs/DB18675
    Investigational

    Ozekibart is a tetravalent recombinant humanized IgG1 agonist antibody targeting the human TRAIL death receptor 5 (DR5). It is being investigated for the treatment of chondrosarcoma.

  3. Drug

    Palopegteriparatide

    go.drugbank.com/drugs/DB18676
    ApprovedInvestigational

    Palopegteriparatide is a prodrug consisting of PTH(1-34) conjugated to a methoxy polyethylene glycol carrier (mPEG) via a proprietary TransCon Linker. … Palopegteriparatide is a parathyroid hormone (PTH) analog.

    Synonyms: oxy-1,2-ethanediyl), α-hydro-ω-methoxy-, ether with N-[[[2-[[6-[[1-[3-[[3-(2,3-dihydroxypropoxy)propyl]amino]-3-oxopropyl]-2,5-dioxo-3-pyrrolidinyl]thio]hexyl]amino]ethyl]amino]carbonyl]-2-methylalanyl-L-seryl-L-valyl-L-seryl-L-α-glutamyl-L-isole, Human parathyroid hormone (PTH) synthetic peptide fragment (1-34), conjugated at the N-terminal amino group via a cleavable linker to O-methylpolyethylene glycol (2 x 20 kDa mPEG); 2-methylalanyl-(1-34
  4. Drug

    MBP134

    go.drugbank.com/drugs/DB18686
    Experimental

    MBP134 is a pan-ebolavirus cocktail comprising two broadly neutralizing human antibodies. It is under investigation for the treatment of Sudan ebolavirus (SUDV).

  5. Drug

    RWJ-800088

    go.drugbank.com/drugs/DB18693
    Investigational

    RWJ-800088 is a synthetic PEGylated thrombopoietin (TPO) mimetic (TPOm) peptide with no sequence homology to endogenous TPO.

    Synonyms: -GLUTAMYLGLYCYL-L-PROLYL-L-THREONYL-L-LEUCYL-L-ARGINYL-L-GLUTAMINYL-3-(2-NAPHTHALENYL)-L-ALANYL-L-LEUCYL-L-ALANYL-L-ALANY, METHOXYPOLYETHYLENEGLYCOL20000-PROPIONYL-L-ISOLEUCYL-L-GLUTAMYL-GLYCYL-L-PROLYL-L-THREONYL-L-LEUCYL-L-ARGINYL-L-GLUTAMINYL-L-2-NAPHTHYLALANYL-L-LEUCYL-L-ALANYL-L-ALANYL-L-ARGINYLSARCOSYL-NE-(METHOXYPOLYETHYLENEGLYCOL20000
  6. Drug

    TN-201

    go.drugbank.com/drugs/DB18700
    Investigational

    TN-201 is a gene therapy comprising a native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and the wild-type human MYBPC3 gene.

    Synonyms: Native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and the wild-type human MYBPC3 gene
  7. Drug

    SHR-A1904

    go.drugbank.com/drugs/DB18702
    Investigational

    SHR-A1904 is under investigation in clinical trial NCT04877717 (A Study of SHR-A1904 in Patients With Advanced Solid Cancer).

  8. Drug

    Efbemalenograstim alfa

    go.drugbank.com/drugs/DB18704
    ApprovedInvestigational

    Efbemalenograstim alfa is a long-acting recombinant fusion protein of granulocyte-colony stimulating factor (G-CSF) due to the addition of the Fc portion of human IgG2, allowing for once-per-cycle administration … the FDA under the brand name Ryzneuta for the treatment of chemotherapy-induced neutropenia in adult patients with non-myeloid malignancies receiving myelosuppressive anti-cancer drugs associated with a

  9. Drug

    Recombinant stabilized RSV B prefusion F antigen

    go.drugbank.com/drugs/DB18714
    ApprovedInvestigational

    The vaccine comprises two antigens - the other being [recombinant stabilized RSV A prefusion F antigen] - which have been expressed in Chinese hamster ovary cell lines and then purified and lyophilized … Recombinant stabilized RSV B prefusion F antigen is one component of a bivalent respiratory syncytial virus (RSV) vaccine called Abrysvo.

  10. Drug

    Pemivibart

    go.drugbank.com/drugs/DB18720
    Investigational

    Pemivibart (Pemgarda) is a human IgG1 monoclonal antibody targeting the SARS-CoV-2 spike protein receptor binding domain.