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TA-CIN
go.drugbank.com/drugs/DB05809InvestigationalTA-CIN is a subunit vaccine comprising L2/E6/E7 proteins from Human Papillomavirus (HPV16), designed to generate a strong cellular immune response against HPV-infected cells.
Managlinat dialanetil
go.drugbank.com/drugs/DB05518InvestigationalCS-917 is a novel inhibitor of fructose 1,6-bisphphosphatase (FBPase) which is one of the rate-limiting enzymes of gluconeogenesis.
Cergutuzumab amunaleukin
go.drugbank.com/drugs/DB14874InvestigationalCergutuzumab amunaleukin is under investigation in clinical trial NCT02004106 (A Study to Evaluate Safety, Pharmacokinetics, and Efficacy of RO6895882 in Participants With Advanced and/or Metastatic Solid
Zalifrelimab
go.drugbank.com/drugs/DB15632InvestigationalZalifrelimab is under investigation in clinical trial NCT03894215 (Phase 2 Study of Anti-pd-1 Independently or in Combination With Anti-ctla-4 in Second-line Cervical Cancer).
Synonyms: A human monoclonal antibody targeting cytotoxic T lymphocyte associated protein 4 (ctla4)Human Lactoferrin Peptide hLF1-11
go.drugbank.com/drugs/DB16245InvestigationalHuman Lactoferrin Peptide hLF1-11 is under investigation in clinical trial NCT00509834 (A Study on the Tolerability and Early Efficacy of Hlf1-11 in Patients With Proven Candidaemia).
Synonyms: N-terminal peptide of human lactoferrin 1-11Pegmusirudin
go.drugbank.com/drugs/DB19220InvestigationalPegmusirudin is under investigation in clinical trial NCT00074620 (A Clinical Study to Assess the Safety of Peg-hirudin (SPP200) Compared to Heparin in Patients Who Are on Haemodialysis).
Concanamycin A
go.drugbank.com/drugs/DB14062ExperimentalConcanamycin A is an H+-ATPase (vacuolar) inhibitor.
Synonyms: Concanamycin AAZD-8330
go.drugbank.com/drugs/DB06061InvestigationalAZD-8330 is a potent, selective, orally active MEK inhibitor that blocks signal transduction pathways implicated in cancer cell proliferation and survival. … AZD-8330 has shown tumor suppressive activity in multiple preclinical models of human cancer including melanoma, pancreatic, colon, lung, and breast cancers.
Zilovertamab vedotin
go.drugbank.com/drugs/DB18457InvestigationalZilovertamab vedotin is an Antibody-drug conjugate (ADC) comprising an anti-ROR1 monoclonal antibody (UC-961), a proteolytically cleavable maleimidocaproyl-valine-citrulline-para-aminobenzoate linker ( … mc-vc-PAB), and a monomethyl auristatin E (MMAE) cytotoxin.